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Pharmaceuticals Dimenhydrinate Raw Materials powder
Product Overview:
Theabenhydramine is a double salt of diphenhydramine and 8-clofylline. The antihistamine effect is weaker than diphenhydramine, and the anti-motion sickness and anti-emesis effect are stronger. It is mainly used to prevent nausea, vomiting, vertigo and Meniere syndrome caused by motion sickness. It is also effective for radiation therapy, pregnancy, post-surgery, inner ear inflammation and various vertigo and vomiting caused by the use of drugs (such as streptomycin).
Pharmaceuticals Dimenhydrinate Raw Materials powder Attributes
CAS:523-87-5
MF:C17H21NO.C7H7ClN4O2
MW:469.97
EINECS:208-350-8
Specification: 99% min Dimenhydrinate powder
Sample:Dimenhydrinate powder
Packaging:1kg/bag, 25kg/drum
From:Henrikang
Appearance:white
Shelf Life: 2 Years
Test Method: HPLC
Pharmaceuticals Dimenhydrinate Raw Materials powder Details
Dimenhydrinate powder Usage and Synthesis.
It is a double salt of diphenhydramine and 8-clofylline. It has the same effect as diphenhydramine hydrochloride, but its antihistamine effect is weaker than the latter. It can inhibit the emetic chemical receptive area of the brain, and has general central inhibition and anticholinergic effects, thus having sedative and antiemetic effects. The absorption is rapid and complete after oral administration, the effect takes 15 to 60 minutes, the effect lasts 3 to 6 hours, the elimination phase half-life (t1/2β) 4-6 hours, and the plasma protein binding rate is high. It is metabolized primarily in the liver and excreted in the urine as metabolites. Patients with liver dysfunction who take this product can produce accumulation in the body and should be reduced.
Drug interaction of Dimenhydrinate powder.
1. Do not drink alcohol after taking the drug, and do not take it with other central nervous depressants.
2. This product can make ethanol, central nervous system inhibitors, tricyclic antidepressants and other synergies. It can briefly affect the absorption of barbiturates and sodium sulfanilate. When used with sodium p-aminosalicylate, the blood concentration of the latter was reduced.
3. Take it with food or milk to reduce the irritation of the stomach.
Pharmacological action of Dimenhydrinate.
Product method of Bulk Dimenhydrinate powder.
