Azathioprine Raw Materials Powder

CAS:446-86-6

MF:C9H7N7O2S

MW:277.26

EINECS:207-175-4

Specification: 99% min Azathioprine Powder

Sample:Azathioprine

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:white

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Azathioprine Powder Usage and Synthesis.

Azathioprine is mainly used for anti-rejection reaction during organ transplantation, and it is mostly used with corticosteroids, or anti-lymphocyte globulin (ALG), and the effect is better. It is also widely used in rheumatoid arthritis, systemic lupus erythematosus, active chronic hepatitis, ulcerative colitis, myasthenia gravis, scleroderma and other autoimmune diseases. In the treatment of chronic nephritis and nephrotic syndrome, its efficacy is not as good as cyclophosphamide. Because of its more serious adverse reactions, the treatment of the above diseases is not used as the drug of choice, usually when corticosteroids alone cannot be controlled.

Uses of Azathioprine.

Azathioprine is one of the derivatives of chemical synthesis 6-mercaptopurine and belongs to immunosuppressive drugs. It is a derivative of mercaptopurine and acts by breaking down into mercaptopurine in the body. It is mainly used to suppress immune rejection during allograft, and is mostly used in combination with corticosteroids. It is also widely used in rheumatoid arthritis, systemic lupus erythematosus, autoimmune hemolytic anemia, thrombocytopenic purpura, active chronic hepatitis, ulcerative colitis, myasthenia gravis, scleroderma and other autoimmune diseases. The blood pattern should be examined strictly during medication. Hepatic insufficiency is prohibited. When combined with corticosteroids, the mouth is prone to viral infections such as herpes zoster, herpes simplex, and chickenpox. Prohibited for pregnant women. Used as immunosuppressive drug, antitumor drug.

Pharmacological action of Azathioprine.

Azathioprine, a derivative of 6-MP, is a commonly used immunosuppressant in clinic. It can significantly inhibit both humoral and cellular immunity and inhibit the synthesis of DNA and RNA. After oral absorption, this product is converted into 6-mercaptopurine in the body, plays an anti-purine metabolic role, prevents lymphocyte proliferation, and produces an immunosuppressive effect. It is mainly used to suppress immune rejection during organ transplantation. Dermatology is used to treat lupus erythematosus, pemphigus, pemphigus, scleroderma, sarcoid, psoriasis, Becset's disease, Purpura, allergic vasculitis, Wegener's granuloma, Mycosis fungoides, pityriasis rubropilaris, atopic dermatitis, fulminant acne, etc. In addition, it is also used in rheumatoid arthritis, ulcerative colitis, myasthenia gravis, chronic nephritis and nephrotic syndrome.

Product method of Bulk Azathioprine Powder.