• Human APIs PowderRespiratory Drugs Raw Material Antiviral Antibacterial Antipyretic Analgesics Antihistamine Drugs Antineoplastic Cosmetic Raw Material
  • Pharmaceutical IntermediatesPharmaceutical intermediates Nutritional Supplements Pharmaceutical raw materials
  • OEM & ODMCapsule Softgel Capsule Gummies Drop & drinks Tables
  • Veterinary raw materialsAntibacterial anti-inflammatory Respiratory Drugs Anthelmintics Antiviral drugs Feed additives
  • About UsCompany profileQualificationQuality AssuranceService teamFactory TourR&D Center
  • Pharmaceutical raw materials Powder Manidipine Dihydrochloride

    • Pharmaceutical raw materials Powder Manidipine Dihydrochloride
    • Pharmaceutical raw materials Powder Manidipine Dihydrochloride storehouse
    • Pharmaceutical raw materials Powder Manidipine Dihydrochloride quality testing
    • Pharmaceutical raw materials Powder Manidipine Dihydrochloride quality testing
    • Pharmaceutical raw materials Powder Manidipine Dihydrochloride certificate

    Product Overview:

    It can block L-type and T-type calcium channels at the same time, and has dilating effect on both entrant and outgoing glomerular arterioles, and has better protective effect on kidney than amlodipine.

    Pharmaceutical raw materials Powder Manidipine Dihydrochloride Attributes

    Manidipine Dihydrochloride Raw Powder

    CAS:89226-75-5

    MF:C35H40Cl2N4O6

    Manidipine Dihydrochloride

    MW:683.62

    EINECS:680-304-3

    Specification​: 99% min Manidipine Dihydrochloride

    Sample:Manidipine Dihydrochloride Powder

    Packaging:1kg/bag, 25kg/drum

    Brand: Henrikang

    Appearance:white

    Storage: Cool Dry Place

    Shelf Life: 2 Years

    Test Method: HPLC

    Pharmaceutical raw materials Powder Manidipine Dihydrochloride Details

    Manidipine Dihydrochloride Usage and Synthesis.

    Manidipine hydrochloride tablets, indicated for hypertension, especially for patients with low renin type hypertension. It is also suitable for those with impaired kidney function. For hypertension, especially for patients with low renin type hypertension. It is also suitable for those with impaired kidney function.

    Manidipine Dihydrochloride powder

    Uses of Manidipine Dihydrochloride.

    Calcium antagonists. It has the function of relaxing arterial smooth muscle, dilating blood vessels, reducing peripheral vascular resistance and arterial pressure. For the treatment of essential hypertension, the effect of lowering blood pressure on low renin type hypertension is more obvious, and can improve uric acid metabolism.

    Manidipine Dihydrochloride

    In vitro study of Manidipine Dihydrochloride.

    At a holding potential of −37mV, Manidipine decreases the CaManidipine concentration-dependent inhibition of calcium ion concentration response at concentrations higher than 0.1nM. Manidipine inhibited coronary and renal arteries with pIC50 of 9.3nM and 9.1nM, respectively. Manidipine partially inhibits sympathetic nerve activity and suppresses mean arterial pressure response to norepinephrine infusion. Manidipine also inhibits aldosterone secretion. Manidipine increases urinary calcium and uric acid. In addition, Manidipine, at nanomolar levels, can effectively regulate the transcription of genes involved in pro-inflammatory changes in mesangial cells.

    Product method of Manidipine Dihydrochloride.

    Our advantage
    Our Factory
    Shipping
    Tel: 86-29-89601602
    WhatsApp: 8613726826401‬
    WeChat: 13022869828
    E-mail: sales28@interlgroup.com
    Add: Fengcheng 2nd Road, Weiyang District, Xi'an, Shaanxi, China
    ©2025 Xi'an Henrikang Biotech Co., Ltd.,