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raw Materials powder Hydroxychloroquine Sulfate
Product Overview:
Hydroxychloroquine sulfate is an anti-malarial drug with anti-inflammatory, immunomodulatory and anticoagulant effects. At present, hydroxychloroquine is mainly used in the clinical treatment of rheumatoid arthritis, juvenile chronic arthritis, discoid lupus erythematosus and systemic lupus erythematosus, but the clinical effect is slow, often taking 2 to 4 months. The pharmacological action of this drug is not very clear, it may be related to the stabilization of lysosomal membrane, inhibition of prostaglandin formation, inhibition of chemotaxis of polymorphonuclear cells and phagocytosis, may interfere with the formation of monocyte interleukin-1 and inhibit the release of neutrophil superoxide.
raw Materials powder Hydroxychloroquine Sulfate Attributes
CAS:747-36-4
MF:C18H28ClN3O5S
MW:433.95
EINECS:212-019-3
Specification: 99% min Hydroxychloroquine Sulfate powder
Sample:Hydroxychloroquine Sulfate powder
Packaging:1kg/bag, 25kg/drum
Brand:Henrikang
Appearance:white
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
raw Materials powder Hydroxychloroquine Sulfate Details
Hydroxychloroquine Sulfate powder Usage and Synthesis.
It has been reported that hydroxychloroquine sulfate tablets are widely distributed in the eyes, kidneys, liver, lungs and other organs after oral administration, and can also pass through the placenta. The blood concentration reaches its peak in about 2 to 4.5 hours, and the concentration in red blood cells is 2 to 5 times higher than the plasma concentration. Some are metabolized in the liver as active deethylated metabolites. The plasma elimination half-life is about 32 days. It is mainly excreted through the kidney and excreted slowly, of which 23-25% is the original drug and can also be excreted with milk.
Uses of Hydroxychloroquine Sulfate.
1, antimalarial: is a common antimalarial drug, can inhibit the malaria parasite, has the effect of reducing disease and preventing recurrence.
2, immunosuppression: has the effect of immunosuppression, for patients with systemic lupus erythematosus, discoid lupus erythematosus has some alleviating effect.
3, anti-rheumatism: It has anti-rheumatism effect after use, which can alleviate the symptoms of joint pain caused by rheumatic diseases.
In addition, it also has anti-inflammatory, analgesic, inhibition of platelet aggregation and other effects, and has the effect of improving the condition.
In vitro study of Hydroxychloroquine Sulfate.
Product Methods of Hydroxychloroquine Sulfate.
