Artemisinin Powder 98% Pure Immune Support

CAS:63968-64-9

MF:C15H22O5

MW:282.33

EINECS:1806241-263-5

Specification​: 99% min Artemisinin Powder

Sample:Artemisinin Powder

Packaging:1kg/bag, 25kg/drum

Brand: Ausreson

Appearance:White powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Artemisinin is a sesquiterpene lactone drug with peroxide groups extracted from the traditional Chinese medicine Artemisia annua. Its effect on the ultrastructure of the erythrocytic stage of mouse Plasmodium is mainly the change of the membrane structure of the Plasmodium. The drug first acts on the food vacuole membrane, the surface membrane, mitochondria, and the endoplasmic reticulum. In addition, it also has a certain effect on the chromatin in the nucleus.

It suggests that the mode of action of artemisinin is mainly to interfere with the function of the surface membrane-mitochondria. It may be that artemisinin acts on the food vacuole membrane, thereby blocking the earliest stage of nutrient intake, causing the Plasmodium to starve for amino acids faster, quickly forming autophagic vacuoles, and continuously excreting them from the parasite, causing the Plasmodium to lose a large amount of cytoplasm and die.

The ingestion of tritium-labeled isoleucine by Plasmodium falciparum cultured in vitro also shows that its initial mode of action may be to inhibit the synthesis of protozoan proteins.

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Use of Artemisinin Powder.

Artemisia annua is used as an antimalarial drug. Clinical applications have shown that artemisinin and its derivatives are effective against paramalaria and malignant malaria, especially artemtherin, which is more effective than other artemisinin drugs in killing asexual bodies in malarial parasites. It has the advantages of high efficiency, rapid effect, low toxicity and no cross-resistance with chloroquine. It can be used not only for treatment but also for emergency treatment.

It is suitable for various malaria, such as malignant malaria, vivax malaria, chloroquine-resistant malaria and cerebral malaria. Including dangerous types. The most eye-catching is dihydroartemisinin and its tablets. The drug has a 10-fold increase in antimalarial efficacy compared to artemisinin, and the recurrence rate is only 1.95%.

Therefore, it was rated as one of the top ten scientific and technological achievements in China in 1992. Artemisinin and its derivatives are not only an excellent antimalarial drug, but also have potential attractive prospects in the treatment of other diseases. Animal experiments have found that artemisinin can kill 100% of the worms in the treatment of mouse Clonorchis sinensis; and the killing rate of 33.8-99.3% in the treatment of animal schistosomiasis.

The total effective rate of artemisinin in treating discoid lupus erythematosus is 90%. The efficacy of artemisinin in treating dengue fever is significantly better than that of western medicines such as morphine. Immunologists have also found in their research that artemisinin can significantly increase the transformation rate of lymphocytes and enhance the immune function of antibodies. No toxic effects on the heart, liver, or kidneys have been found. There are no obvious side effects in clinical practice.

Extraction method of Artemisinin Powder.

Take Artemisia annua, add water 10 times the weight of Artemisia annua medicinal material, soak for 0.5h, decoct for 1 hour, filter, add water 8 times the weight of the medicinal material to the residue, decoct for 1 hour, filter out the medicinal liquid, combine the two decoctions, concentrate to a relative density of 1.05 at 60°C, add ethanol to make the volume percentage of alcohol content reach 75%, stir, let stand, filter, concentrate the filtrate to a relative density of 1.25 at 65°C, and recover ethanol to obtain a concentrated solution, purify it with a macroporous resin, collect the eluate, continue to concentrate, and dry the concentrated solution to obtain an artemisinin extract.

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