Natural Plant Extract Bulk Baicalin Powder

CAS:21967-41-9

MF: C21H18O11

MW:446.36

EINECS:606-866-1

Specification: 99% min Baicalin Powder

Sample: Baicalin Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: Pale Yellow to Yellow

Storage: Store at -20°C

Shelf Life: 2 Years

Test Method: HPLC

Baicalin Powder Usage and Synthesis.

Baicalin is a kind of flavonoid compound extracted from the root of Scutellaria baicalensis, which is a light yellow powder with bitter taste at room temperature. It is insoluble in methanol, ethanol, acetone, slightly soluble in chloroform and nitrobenzene, almost insoluble in water, soluble in hot acetic acid.

It shows green colour when met with ferric chloride and produces orange precipitate when met with lead acetate. When dissolved in alkali and ammonia, it shows yellow colour at the beginning, and soon turns into black brown colour.

Has significant biological activity, with antibacterial, diuretic, anti-inflammatory, cholesterol, anti-thrombosis, relief of asthma, laxative detoxification, haemostasis, foetal protection, anti-metamorphosis and antispasmodic effects, but also for the mammalian liver salivary enzyme specific inhibitors, with the regulation of certain diseases, but also has a strong anti-cancer response to physiological efficacy.

Mainly used in the treatment of dampness, summer temperature, chest congestion and vomiting, damp-heat plagued, diarrhoea and jaundice, lung fever and cough, high fever and thirst, blood fever and vomiting, carbuncle, swelling and sores, foetal restlessness.

In addition, baicalin can absorb ultraviolet rays, remove oxygen free radicals and inhibit the generation of melanin, which is a good functional cosmetic raw materials.

Uses and functions of Baicalin.

It has a broad-spectrum antibacterial effect, as well as choleretic, anti-inflammatory, anti-metamorphic, antipyretic, detoxification, diuretic, antihypertensive and other effects.

Clinically used in the treatment of infectious hepatitis, to reduce hepatitis in the active phase of ghrelin transaminase has good efficacy, but also used in the treatment of stroke and paralysis, can reduce cerebral vascular resistance, increase cerebral blood flow, improve the permeability of the blood-brain barrier and to fight against adenosine phosphate-induced platelet aggregation.

A key flavonoid compound found in Scutellaria baicalensis root has antioxidant, anti-inflammatory, anti-tumour and anti-apoptotic activities.

Used in the treatment of infectious hepatitis, acute jaundice and chronic hepatitis, acute biliary tract infections, lead poisoning, etc.

Physical and Chemical Properties of Baicalin.

Yellow crystal, melting point 223°C. Pale yellow fine needle crystals (methanol), melting point 223-225 ° C, [α]18D + 123 ° C (c = 0.2, pyridine - water); soluble in N, N - dimethylformamide, pyridine, soluble in sodium bicarbonate, sodium carbonate, sodium hydroxide and other alkaline solutions, but in alkaline solution is not stable, gradual change to a dark brown, slightly soluble in hot glacial acetic acid, difficult to dissolve in formic acid, acetic acid, acetone, almost insoluble in water. Ether, benzene, chloroform, etc.

In vitro studiesof  Bulk Baicalin Powder.