Griseofulvin raw material Griseofulvin Powder 126-07-8

CAS:126-07-8

MF:C17H17ClO6

MW:352.77

EINECS:204-767-4

Specification: 99% min Griseofulvin Powder

Sample:Griseofulvin Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Griseofulvin Powder Usage and Synthesis.

Griseofulvin is a non-polyene antifungal antibiotic, it can strongly inhibit the mitosis of fungal cells, interfere with fungal DNA synthesis, and it binds to microtubule proteins, which can prevent fungal cell division.

It has been widely used in the treatment of fungal infections of the skin and stratum corneum since 1958, and has strong inhibitory effect on red ringworm, broken ringworm, and Lucerne trichothecenes.

Ashwagandha is not only a commonly used antibiotic for the clinical treatment of fungal infections of the skin and stratum corneum, but it is also used in agriculture for the control of fungal diseases, and it is particularly effective against a type of Candidiasis of apples that can be caused by infections at the time of pollination of flowers.

Ashwagandha is indicated for the treatment of various ringworm diseases, including tinea capitis, tinea unguium, tinea corporis, tinea cruris, tinea pedis and tinea cruris. It should not be used for mild, limited superficial fungal infections and where topical antifungals have been effective.

Ashwagandha is ineffective against Candida, Histoplasma, Actinomyces, Sporothrix, Bacillus, Coccidioides, Nocardia and Cryptococcus infections and ringworm.

Uses and functions of Griseofulvin.

Griseofulvin inhibits a wide range of dermatophytes, including S. dermatitidis, S. dermatitidis, and S. microsporum. It is ineffective against lichen planus, Candida albicans and bacteria.

Griseofulvin acts as a bacteriostat and is effective against actively growing fungi.

Griseofulvin is used for ringworm of the head, onychomycosis, tinea capitis, tinea pedis and tinea corporis caused by sensitive fungi.

It has inhibitory effect on all kinds of dermatophytes, and is effective for the fungi with vigorous growth. It is suitable for the treatment of all kinds of ringworm, including tinea capitis, tinea unguium, tinea corporis, tinea cruris, tinea pedis and tinea cruris.

Pharmacological Effect of Griseofulvin.

In medicine, this product mainly has good antimicrobial effect on superficial fungi such as Trichophyton, Microsporum, S. epidermidis and so on.

It has no antimicrobial effect on Candida, Cryptococcus, Histoplasma, Sporothrix, Bacillus and Coccidioides. The drug inhibits the growth of fungi by interfering with their nucleic acid synthesis.

In agriculture, this product has inhibitory effect on ascomycetes, stretcher fungi, hemipterous fungi and some algal fungi, and only has no effect on oomycetes with no chitin in the cell wall.

After spraying melons and other crops, it can enter into branches, leaves, fruits and other parts of the body through endosorption and conduction, root absorption of aqueous solution and transpiration, etc., to prevent and control fungal diseases. According to the research of Briau and others (1946), the concentration of grey mycotoxin can make the mycelium of Bctrytisallill and other mycelia stout and deformed even if the concentration of grey mycotoxin is as low as 10mg/L or even 1mg/L. The mycelium is bent in a spiral shape, and there are many abnormal branches. A large number of abnormal branches; has sprouted conidia development block, lose apical dominance; thus on a variety of plant diseases, especially on powdery mildew, grey mould with endosorbent therapeutic activity, bacteriostatic activity is more prominent than bactericidal activity.

Production Method of Bulk Griseofulvin Powder.

Penicillin grey is an antibiotic extracted from the fermentation broth of Penicilli-um griseofulvum (Penicillium griseofulvum).