• Human APIs PowderRespiratory Drugs Raw Material Antiviral Antibacterial Antipyretic Analgesics Antihistamine Drugs Antineoplastic Cosmetic Raw Material
  • Pharmaceutical IntermediatesPharmaceutical intermediates Nutritional Supplements Pharmaceutical raw materials
  • OEM & ODMCapsule Softgel Capsule Gummies Drop & drinks Tables
  • Veterinary raw materialsAntibacterial anti-inflammatory Respiratory Drugs Anthelmintics Antiviral drugs Feed additives
  • About UsCompany profileQualificationQuality AssuranceService teamFactory TourR&D Center
  • Azithromycin Raw Materials Azithromycin Powder

    • Azithromycin Raw Materials Azithromycin Powder
    • Azithromycin Raw Materials Azithromycin Powder storehouse
    • Azithromycin Raw Materials Azithromycin Powder quality testing
    • Azithromycin Raw Materials Azithromycin Powder quality testing
    • Azithromycin Raw Materials Azithromycin Powder certificate

    Product Overview:

    Azithromycin is a kind of antibiotic drug with wide clinical application, with the advantages of wide antibacterial spectrum, little stimulation to the gastrointestinal tract and fast oral absorption, which is used by both adults and children. Azithromycin because of side effects less than cephalosporin antibiotics, has been the most commonly used in China's hospital clinics for the treatment of bacterial infection-related diseases of an antibiotic class of drugs, this drug is a second-generation semi-synthetic derivatives of macrolides, structurally different from erythromycin, which is inserted in the erythromycin lactone ring at the 9a position of a methyl-substituted nitrogen, thus producing a 15 yuan macrolide

    Azithromycin Raw Materials Azithromycin Powder Attributes

    Azithromycin Raw Materials Azithromycin Powder

    CAS:83905-01-5

    MF:C38H72N2O12

    Azithromycin

    MW:748.98

    EINECS:617-500-5

    Specification​: 99% min Azithromycin Powder

    Sample:Azithromycin Powder

    Packaging:1kg/bag, 25kg/drum

    Brand: Henrikang

    Appearance: White to Off-White

    Storage: Cool Dry Place

    Shelf Life: 2 Years

    Test Method: HPLC

    Azithromycin Raw Materials Azithromycin Powder Details

    Azithromycin Powder Usage and Synthesis.

    Azithromycin has a mechanism of action similar to that of erythromycin, exerting its antibacterial effect by binding to the 50S subunit of the ribosome of sensitive bacteria and inhibiting RNA-dependent protein synthesis, retaining the typical antibacterial spectrum of erythromycin. The activity against Chlamydia is similar to that of erythromycin.

    Compared with erythromycin, the antibacterial activity against gram-negative bacteria has been significantly improved, the antibacterial activity against H. influenzae and Neisseria gonorrhoeae is more than 4 times stronger than that of erythromycin, the antibacterial activity against Legionella is about 2 times stronger, and the antibacterial activity against Enterobacteriaceae is also significantly stronger than that of erythromycin.

    The MIC for most gram-negative bacteria is less than 1μg/ml.Staphylococcus aureus and Streptococcus pyogenes are cross-resistant to this product and erythromycin. It also has good killing effect on Toxoplasma gondii and syphilis spirochetes.

    Azithromycin is mainly used for respiratory tract infections, genitourinary tract infections, soft tissue skin infections and sexually transmitted diseases caused by sensitive microorganisms.

    Azithromycin Powder

    Uses of Azithromycin.

    Antibiotics for infections caused by sensitive bacteria, such as respiratory infections, skin and soft tissue infections.

    Used for respiratory tract infections, urinary tract infections, skin and soft tissue infections and sexually transmitted diseases

    1. For acute pharyngitis, acute tonsillitis caused by Streptococcus pyogenes, sinusitis, acute otitis media,acute bronchitis, acute exacerbation of chronic bronchitis caused by sensitive bacteria.

    2. For pneumonia caused by Streptococcus pneumoniae, H. influenzae and Mycoplasma pneumoniae.

    3. For urethritis, cervicitis and pelvic inflammatory disease caused by Chlamydia and non-multi-resistant Neisseria gonorrhoeae, and simple genital infections caused by non-multi-resistant gonococcus (co-infections with spirochetes of Treponema pallidum should be excluded).

    4. For skin and soft tissue infections caused by sensitive bacteria.

    Azithromycin

    Drug interactions of Azithromycin.

    (1) Azithromycin should not be taken with antacids containing aluminium or magnesium, the latter can reduce the peak blood concentration of the product by 30%, but no effect on the total bioavailability has been seen; must be combined, the product should be given 1 hour before or 2 hours after taking the above drugs.

    (2)When combined with theophylline, it can increase the concentration of the latter in the plasma; attention should be paid to the detection of plasma theophylline levels.

    (3) When combined with warfarin, attention should be paid to checking the prothrombinogen time.

    (4) Close observation of patients is recommended when azithromycin is used concomitantly with the following drugs:Digoxin: It has been reported that certain macrolide antibiotics may reduce the enteric metabolism of digoxin; therefore, when the two drugs are used together, attention should be paid to the possibility of elevated digoxin blood concentrations.

    Ergotamine or dihydroergotamine: acute ergot toxicity with symptoms of severe peripheral vasospasm and dullness of sensation (pain on touch).

    Triazolam: pharmacological effects of triazolam are enhanced by reducing its degradation.Cytochrome P450 system metabolising drugs a raise serum levels of carbamazepine, terfenadine,cyclosporine, cyclohexabarbital, phenytoin.

    (5) The combination of azithromycin and rifabutin increases the toxicity of the latter.

    Azithromycin Raw Powder

    Production Methods of Azithromycin.

    Erythromycin A is used as raw material, which is oximilated and then subjected to Beckmann rearrangement under the action of hydrochloric acid, then dehydrated, reduced and methylated to obtain azithromycin.

    Our advantage
    Our Factory
    Shipping
    Tel: 86-29-89601602
    WhatsApp: 8615091775531
    WeChat: 15091775531
    E-mail: sales21@interlgroup.com
    Add: Fengcheng 2nd Road, Weiyang District, Xi'an, Shaanxi, China
    ©2023 Xi'an Henrikang Biotech Co., Ltd.,