Hydrocortisone Acetate raw material Hydrocortisone Acetate Powder 50-03-3

CAS:50-03-3

MF:C23H32O6

MW:404.5

EINECS:200-004-4

Specification: 99% min Hydrocortisone Acetate Powder

Sample:Hydrocortisone Acetate Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White to Off-White

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Hydrocortisone Acetate Powder Usage and Synthesis.

Hydrocortisone acetate is mainly used for the treatment of rheumatoid arthritis, rheumatic fever, gout, and bronchial asthma. The injection is used for tuberculous or purulent meningitis, tuberculous pleurisy, pyothorax, arthritis, tenosynovitis, tendon strain, sprain, nodular itchy rash, lichen planus, etc. Eye drops are used for all kinds of ophthalmia. Creams are used for allergic or seborrheic dermatitis, pruritus, etc.

Drug interactions of Hydrocortisone Acetate.

1、Combination of this product with barbiturates, antiepileptic drugs, aminoglycosides, rifampicin may lead to a decrease in the effect of this product.

2、Combination of this product with potassium-excreting diuretics may promote potassium excretion, and attention should be paid to potassium supplementation.

3、Combination with anticoagulants may reduce the effect of the latter.

4、Combining with salicylic acid can cause peptic ulcer.

5、This product may increase blood sugar and weaken the effect of hypoglycaemic drugs or insulin.

Pharmacological Effect of Hydrocortisone Acetate.

Hydrocortisone acetate injection, hydrocortisone acetate tablets:

This product is an adrenocorticotropic hormone drug. It has a variety of pharmacological effects such as anti-inflammatory, anti-allergic and immune suppression.

1, anti-inflammatory effect: glucocorticoids reduce and prevent the tissue response to inflammation, thus reducing the manifestation of inflammation

2, Immunosuppressive effect: prevent or inhibit cell-mediated immune response, delayed allergic reaction, and reduce the expansion of the primary immune response.

3、Anti-toxicity, anti-shock effect: glucocorticoids can counteract the stimulatory response of bacterial endotoxin on the body, reduce cellular damage, and play a role in protecting the body.

Hydrocortisone acetate cream:

Topical use has: anti-inflammatory, anti-allergic, anti-proliferative, anti-itching and reduce oozing effect; can reduce and prevent the tissue response to inflammation, can eliminate local non-infectious inflammation caused by fever, redness and swelling, thus reducing the manifestation of inflammation; immunosuppressive effect: to prevent or inhibit cell-mediated immune response, delayed allergic reaction, and reduce the expansion of the primary immune response.

Hydrocortisone acetate eye drops, Hydrocortisone acetate eye ointment:

This product is a glucocorticoid hormone drug. It has anti-inflammatory and anti-allergic effects, inhibits the proliferation of connective tissue, reduces the permeability of capillary walls and cell membranes, reduces inflammatory exudation, and inhibits the release of histamine and other allergic mediators.

Product Method of Bulk Hydrocortisone Acetate Powder.

Hydrocortisone and acetic anhydride are esterified in pyridine.