Raw Materials Deer Antler Extract powder

CAS:90045-36-6

MF:/

MW:/

EINECS:289-896-4

Specification: 99% min Deer Antler Extract Powder

Sample:Deer Antler Extract Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: Brown

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Deer Antler Extract Powder Usage and Synthesis.

Ginkgo biloba extract is the dried leaf extract of Ginkgo (GinkgobilobaL.), a plant of the Ginkgoaceae family, the main components of which are flavonoids and terpene lactones, which

have a variety of health functions and are widely used in food and cosmetics.

Uses and functions of Deer Antler Extract.

Ginkgo biloba has the effects of activating blood circulation, removing blood stasis and opening up the channels. Extracts of Ginkgo biloba are widely used clinically to improve arteriosclerosis of

the cardiovascular and cerebrovascular vessels, as well as to improve microcirculation of the brain.

It can be used to treat chest paralysis caused by heart yang deficiency, as well as hemiplegia,aphasia and hemiplegia in cerebral stroke.

It can also improve blood circulation in the middle cerebral artery and vertebral artery. Therefore,it can be used to treat dizziness, tinnitus, and cerebral blood supply deficiency.

It can also be used to treat chronic venous thrombosis and phlebitis in the veins of the lower limbs.

Pharmacological Effect of Deer Antler Extract.

1、Antagonism of PAF: Competitively bind to the membrane receptor of PAF and antagonise the action of PAF, thus inhibiting platelet aggregation, endothelial cell permeability, bronchial smooth muscle contraction and inflammatory response.

2、Scavenging effect of free radicals: It can remove excessive free radicals in the organism and inhibit lipid peroxidation of cell membrane, thus protecting the cell membrane and preventing a

series of injuries caused by free radicals to the organism, such as thrombosis, inflammation and atherosclerosis.

3、Adjustment effect on circulatory system: By stimulating the release of catecholamines and inhibiting their degradation, as well as by stimulating the generation of prostacyclin and

endothelial diastolic factor to produce arterial diastolic effect, together to maintain arterial and venous vascular tone.

4、Haemodynamic improvement effect: It has the effect of reducing the viscosity of whole blood,enhancing the plasticity of red blood cells and white blood cells, and improving blood circulation.

5、Tissue protection effect: increase the supply of oxygen and glucose to ischemic tissues,increase the number of brain muscarinic receptors and the renewal of norepinephrine, as well as

enhance the function of certain central cholinergic system.

Drug interactions of Bulk Deer Antler Extract Powder.

Ginkgo biloba extract is a commonly used drug in the treatment of cardiovascular diseases, often combined with antiplatelet, sedative, antihypertensive and lipid-lowering drugs.

Ginkgo and its monomer components quercetin, kaempferol and isorhamnetin and other flavonoids have inhibitory effect on CYP3A4, CYP2C9, CYP2B6, etc., and its monomer components

ginkgolides A, B and bilobalide and other lactones have inducing effect on CYP1A2, CYP2B1/2,CYP3A2, CYP2C19, UGT1A1, etc., and are P -glycoprotein substrate, and drug co-use is easy to

trigger drug interactions, and the role of the complex, so need to attract extensive attention.

In recent years, there have been reports of individual cases of bleeding caused by taking ginkgo biloba preparations or combining with other anticoagulant drugs.

Ginkgo biloba extract inhibits PAF and causes bleeding, of which ginkgolide B is considered to be the most important component in inhibiting PAF. However, there are no corresponding controlled studies.Currently commercially available ginkgo biloba products vary widely in composition and amount.

The dose as well as the exact amount of ginkgolide B associated with bleeding is still unknown.Moreover, there may be other ingredients in the products that are capable of causing bleeding.

Therefore, further research in this area is needed.

Therefore, based on the results of the current study, cases of bleeding caused by Ginkgo biloba extract preparations should be communicated to physicians to draw sufficient attention.

And try to avoid ginkgo biloba extract preparations with anticoagulant drugs such as aspirin and warfarin.