Raw Materials Hanfangchin B Powder

CAS:33889-68-8

MF:C37H40N2O6

MW:608.72

EINECS:/

Specification: 99% min Hanfangchin B

Sample:Hanfangchin B powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:White

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Hanfangchin B Powder Usage and Synthesis.

Hantahexin B is an alkaloid with a variety of pharmacological effects. It can relieve inflammation and pain, and has some anti-inflammatory effects on formaldehyde arthritis in rats, but not as much as hanfenhexigenin.

In addition, hanfengzhi ethin can lower blood pressure, inhibit collagen-induced platelet aggregation, and has anti-tumour effects. Hantahexaethylene is present in many traditional Chinese medicines, such as hantahexa and powdered hantahexa.

Uses and functions of Hanfangchin B.

Hambucus et rhizome is a compound with anticancer activity isolated from hambucus. It inhibits the proliferation of breast adenocarcinoma by inducing apoptosis. In addition, it has been shown to inhibit the replication of hiv-1 virus.

Pharmacological Effect of Hanfangchin B.

1. Anti-inflammatory and analgesic effect: HANDFENGJI B has some anti-inflammatory effect on formaldehyde arthritis in rats, but not as good as HANDFENGJI METHYL. Hot plate method and electrical stimulation of the tail root method have proved that hanfengzhi ethylin has a certain analgesic effect on mice, but weaker than hanfengzhi methylin. Antihistamine benzylamine can significantly enhance the analgesic effect of hanfenhexigenin.

2. Antihypertensive effect: 3mg/kg HANPHUIJI BETAIN intravenous, intramuscular injection or gavage can make the anaesthetised cat's blood pressure drop significantly, but not as big as HANPHUIJI METHYLENE and long-lasting, the drop in blood pressure can be seen at the same time, the temporary cardiac contractile force weakening, and often cause the heart rate to slow down.

3. Anti-tumour effect: Hantahexin B has cytotoxic activity on Hela cells (HD) in vitro, and its ED50 is 4.1ug/ml.

4. Other effects: Hantahexaethylene has the effect of inhibiting collagen-induced platelet aggregation. [Toxicity: The LD50 for intraperitoneal injection in mice is more than 50mg/kg.

In vivo studies of Bulk Hanfangchin B Powder.

Fangchinoline attenuates morphine(SC)-induced analgesia in a concentration-dependent manner, and intraperitoneal injection of 30mg/kg and 60mg/kg was effective in the tail-flicktest in mice, but not in the tail-pinchtest.

Fangchinoline attenuated morphine (SC)-induced analgesia in a concentration-dependent manner, with significant effects of intraperitoneal injections of 30 mg/kg and 60 mg/kg in the tail-flicktest but no effect in the tail-pinchtest in mice.