Luteolin Raw Materials Luteolin Powder

CAS:491-70-3

MF:C15H10O6

MW:286.24

EINECS:207-741-0

Specification​: 99% min Luteolin Powder

Sample:Luteolin Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: Light Yellow

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Luteolin Powder Usage and Synthesis.

Lignan is a very representative natural flavonoids, belongs to the weak acidic tetrahydroxyflavonoids, widely distributed in the plant world, mainly found in honeysuckle, chrysanthemum, thorns, white hairy Xiakuqiuqiao and other medicines, thyme, Brussels sprouts, cabbage, cauliflower, beetroot, cabbage and carrots and other vegetables.

This product has the effect of suppressing cough and expectorant. Cough suppressant effect is to inhibit the cough centre; expectorant effect and the product can promote the secretion of respiratory glands and make the phlegm in the acidic mucopolysaccharide dissolution. There are also anti-inflammatory, anti-allergic and immune-enhancing effects.

Uses and functions of Luteolin.

A polyphenol compound that belongs to the flavonoid group. It is a strong antioxidant and free radical scavenger.

Used as cough suppressant, expectorant and anti-inflammatory.

This product has the effect of suppressing cough and expectorant. Cough suppressant effect is to inhibit the cough centre; expectorant effect and the product can promote the secretion of respiratory glands and make the phlegm in the acidic mucopolysaccharide dissolution. There are also anti-inflammatory, anti-allergic and immune-enhancing effects.

It also has antibacterial effect on Aureus, S. pneumoniae and Pseudomonas aeruginosa. Used for chronic bronchitis and other phlegmatic respiratory diseases.

Pharmacological Effect of Luteolin Powder.

1. Anti-tumour: the inhibitory effect of lignocaine on the proliferation of tumour cells is mainly through the inhibition of intracellular activity of certain kinases and blockage of the cell cycle and so on.

2. Antioxidant: the antioxidant effect of lignocaine is mainly manifested in its own oxidation reaction as a reducing agent, enhancing the activity of the organism's antioxidant system and so on.

3, anti-inflammatory: the anti-inflammatory activity of lignocaine is mainly manifested in its ability to reduce the activity of inflammatory factor transcriptional regulator, reduce the production of pro-inflammatory cytokines and inflammatory mediators.

4, neuroprotective effect: lignocaine has a protective effect on the learning and memory ability of the nervous system.

5, anti-fibrosis: lignocaine can reduce the degree of hepatic fibrosis, reduce the content of hydroxyproline (HYP), malondialdehyde (MDA) and the expression of type I pre-collagen mRNA in liver tissues, and in vitro can inhibit the proliferation of hepatic stellate cells (HSC) and collagen synthesis.

And it can improve the histopathological changes of pulmonary fibrosis caused by bleomycin, reduce the lung weight index, significantly reduce the elevation of MDA, HYP, and inhibit the expression of mRNA of transforming growth factor-β1 (TGF-β1) in lung tissues, and in vitro it can inhibit the proliferation of human embryonic lung fibroblasts and promote their apoptosis.

6, anti-fertility and hormone effects: lignocaine has a significant dose-dependent anti-attachment activity, after oral administration can significantly increase the weight and diameter of the uterus, the thickness of the endometrium and the height of its epithelial cells, applied alone with estrogen-like effect, but and ethinyl estradiol in combination with the show has an anti-estrogenic effect.

7, other: lignocaine can inhibit a variety of bacteria and viruses, such as Staphylococcus aureus, Escherichia coli, herpes simplex virus, poliovirus, coxsackie B3 virus. It can inhibit the activity of HIV-1 integrase of AIDS virus and has potential anti-HIV effect.

Lignans can bind to the s2 protein of Severe Acute Respiratory Syndrome (SARS) coronavirus, thus inhibiting the virus from entering the host cells.

Lignans also have anti-Duchenne Leishmania protozoa effects, inhibiting the growth of Duchenne Leishmania protozoa by inhibiting its topoisomerase I and topoisomerase II. In addition, lignans also have immunomodulatory effects, etc.

Extraction method of Bulk Luteolin Powder.

The methods reported in the literature for the extraction of lignocaine, an active ingredient of peanut shells, include solvent method, ultrasonic method, microwave method and supercritical CO 2 method, etc. Among them, the solvent extraction method has been reported more, and most of the solvent extraction methods use methanol, acetone and ethyl acetate as the solvents for the extraction.