98% HPLC Catalpol raw powder manufacturer

CAS: 2415-24-9

MF: C15H22O10

MW: 362.33

EINECS: 219-324-0

Specification​: 99% min Catalpol Powder

Sample: Catalpol Powder Avaliable

Packaging: 1kg/bag, 25kg/drum

Brand: Ausreson

MOQ: 1 kg

Appearance: White powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Last updated: March 2026

Catalpol Powder Usage and Synthesis.

Catalpol is an active ingredient extracted from the traditional Chinese medicine Di Huang. It has the effects of hypoglycaemia, protection of pancreatic islet cells and improvement of insulin resistance.

In addition, catalpol has pharmacological effects such as antioxidant, anti-inflammatory, anti-tumour and analgesic.

In diabetic cardiomyopathy, catalpol can regulate myocardial oxidation-related proteins, reduce stress levels, and improve cardiac diastolic function.

In conclusion, catalpol is a kind of traditional Chinese medicine with various pharmacological effects, which has a positive impact on human health.

How Catalpol Rewires the Body

• Upregulating BDNF/GDNF Expression: Catalpol directly stimulates the production of Brain-Derived Neurotrophic Factor (BDNF). In 2026, this is known as "Synaptic Priming," essential for learning, memory, and repairing damaged neural circuits after injury.

• Inhibiting Pro-Inflammatory Cytokines: It targets the $NF-\kappa B$ and $P38\ MAPK$ pathways, effectively shutting down the inflammatory cascade that leads to brain fog and cognitive decline.

• Mitochondrial Protection: Catalpol stabilizes the mitochondrial membrane potential in neurons, preventing Apoptosis (programmed cell death) during periods of high oxidative stress.

• Diabetic Kidney & Nerve Protection: In 2026, it is a leading research tool for reducing Podocyte injury in kidneys and preventing peripheral neuropathy by lowering advanced glycation end-products (AGEs).

Uses of Catalpol.

The primary function is to stimulate the production of adrenocorticotropic hormone, which increases the productive hormone. Catalpol also has anti-inflammatory activity and has been shown to increase the production of androgens produced by the adrenal glands, leading to increased muscle mass.

Why "98% HPLC Standardized Isolate" is the 2026 Quality Standard

1. Fresh-Root Extraction: Catalpol is highly sensitive to heat and processing (the "blackening" of Rehmannia indicates Catalpol loss). 2026's gold-standard Catalpol Powder is derived via Freeze-Drying or Low-Temperature Membrane Extraction from fresh, un-steamed roots.

2. Pharmacological Purity (≥ 98%): For targeted neuro-research and high-end nutraceuticals, 2026 standards require 98% HPLC purity, ensuring that the therapeutic effect isn't diluted by raw plant sugars or starches.

3. Hygroscopic Stability: Premium 2026 powders are processed to minimize moisture absorption, featuring a stable crystalline structure that ensures a 24-month shelf life without degradation.

Pharmacological effect of Catalpol.

Catalpol is a cyclic enol ether terpene glycoside with blood glucose-lowering and delayed-acting moderating and laxative effects, and is the main component in the hypoglycaemic properties of Dioscorea digitata of the family Xanthophyllaceae. In addition catalpol also has anti-cerebral ischaemic injury, anti-Alzheimer's disease, anti-cancer, anti-hepatitis virus, antispasmodic, inhibit capillary permeability and other activities.

Frequently Asked Questions

In 2026, we clarify: Standard Rehmannia extract (especially the "Prepared/Black" kind) contains almost no Catalpol. Catalpol powder is a highly concentrated isolate from the fresh plant, specifically focused on neuro-regeneration and blood sugar modulation.

Yes. 2026 clinical data suggests that Catalpol promotes Angiogenesis (new blood vessel growth) and reduces the size of cerebral infarctions by protecting neurons from ischemia-related death.

While it has mild hypoglycemic effects, in 2026 it is primarily used for its Protective Effects—it helps prevent the organ damage (eyes, kidneys, nerves) that occurs even when blood sugar is controlled.

For the 98% isolate, the research-backed dosage typically ranges from 50mg to 150mg per day, depending on the specific health objective.

Производитель сырого порошка каталпола с чистотой 98% (по данным ВЭЖХ)
Fabricant de poudre brute de catalpol à 98 % (par HPLC)
Hersteller von rohem Catalpol-Pulver mit 98 % Reinheit (HPLC)
Fabricante de polvo crudo de catalpol al 98 % (por HPLC)
Fabricante de pó bruto de catalpol com 98% de pureza (por HPLC)