Raw Materials Genistein Powder

CAS:446-72-0

MF:C15H10O5

MW:270.24

EINECS:207-174-9

Specification: 99% min Genistein

Sample:Genistein powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:White

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Genistein Powder Usage and Synthesis.

Goldfinch isoflavone, also known as genistein, is a polyphenolic compound that can be found in plants such as soybeans and red clover, with a molecular structure similar to 17β-estradiol, antioxidant properties and a high affinity for the estrogen receptor, which inhibits the activity of tyrosine protein kinase (PTK) and topoisomerase II, and has the effect of inducing programmed cell death, increasing the efficacy of anticancer drugs, and inhibiting angiogenesis, it is a type of flavonoid (also called isoflavone).

Often found with isoflavones called soy glycogen, they are both known as soy isoflavones. These compounds have been extensively studied for their health benefits and are a promising cancer chemopreventive agent with significant impact in the prevention of cancer and other diseases.

Genistein is the main phytoestrogen being studied.

Uses and functions of Genistein.

Genistein has estrogenic and anti-estrogenic properties, has antioxidant effects, can inhibit the activity of tyrosine protein kinase (PTK), can inhibit the activity of topoisomerase II, has the ability to induce programmed cell death, improve the efficacy of anticancer drugs, and inhibit angiogenesis, which makes it a promising cancer chemopreventive agent, and its anticancer effects and mechanisms have a wide range of application prospects.

Pharmacological effect of Genistein.

Goldfinch isoflavones have a polyphenol hydroxyl structure, the hydrogen atom on the phenolic hydroxyl group is easy to detach from the oxygen atom under external action, forming hydrogen ions and exerting a reducing effect, which is the structural basis for genistein's ability to be an antioxidant and have a reducing effect.

Therefore, such substances in food can fight against superoxide anion free radicals, block the chain reaction of free radicals, and play an antioxidant role. Genistein is not a hormone, but it is called a phytoestrogen because of its ability to bind to the estrogen receptor to exert a weak estrogenic effect.

Because the activity of isoflavones is 1/1000 of estradiol, and estradiol competitive binding estrogen receptor, showing two-way regulation, the estrogenic effect is much lower than the harmful effect of estradiol, and thus has a protective effect on hormone-related diseases, such as menopausal syndrome, osteoporosis, elevated blood lipids, etc.; for high estrogen levels, the performance of anti-estrogenic activity to prevent and control breast cancer, endometritis, has a two-way regulation, and has a two-way regulation of endometritis. endometritis, with two-way regulation and balance function.

Goldfinch isoflavones on trinitrotoluene WR1339-induced hyperlipidaemia in rats, there is a reduction in its serum cholesterol and triglyceride effect, for the latter is particularly significant.

Characteristic of Bulk Genistein Powder.

Pale yellow dendritic needle crystal powder. mp297°C-298°C; soluble in commonly used organic solvents, almost insoluble in water, soluble in dilute alkali yellow.