Liquiritigenin Raw Materials Liquiritigenin Powder

CAS:578-86-9

MF:C15H12O4

MW:256.25

EINECS:/

Specification: 99% min Liquiritigenin

Sample:Liquiritigenin Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:White

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Liquiritigenin Powder Usage and Synthesis.

Glycyrrhizin is a flavanone compound is a natural sweetener, sweetness of sucrose 200-500 times, but has a special flavour, with sucrose, saccharin with better results.

In addition, glycyrrhizin also has the role of aroma, a small amount of glycyrrhizin and sucrose can be used with 20% less sucrose, while the sweetness remains unchanged.

Glycyrrhizin is widely used in food industry, it can be used in pickled products instead of sugar to avoid fermentation, discolouration, hardening and other phenomena occurring when sugar is added.

Uses of Liquiritigenin.

Glycyrrhizin is a constituent of liquorice, which has a variety of effects and actions. Firstly, glycyrrhizin has an adrenocorticotropic hormone-like effect, which can inhibit histamine-induced gastric acid hypersecretion and has the effect of antacid and relieving gastrointestinal smooth muscle spasm.

Secondly, glycyrrhizin has obvious antitussive and expectorant effects, and its intensity of action is glycyrrhizic acid>glycyrrhizin flavonoids>glycyrrhizin infusion.

In addition, glycyrrhizin has an anti-inflammatory effect, which protects the inflamed larynx and tracheal mucosa. Glycyrrhizin also has a detoxifying effect on certain poisons similar to glucuronic acid.

In addition, glycyrrhizin can balance the hormone levels in women's bodies and help regulate hormones.

Glycyrrhizin also has anticancer properties, blocking the growth of tumours induced by carcinogens. In short, glycyrrhizin is an important ingredient with a variety of benefits and effects.

In addition, Pueraria Mirifica also contains glycyrrhizin, and its flavonoids include more than 10 kinds of soybean (soybean) glycosides, soybean glycosides, and geranylgeranyl, as well as carotenoids, amino acids, coumarins, and so on.

The flavonoids proposed in Pueraria Mirifica can increase blood flow to the brain and coronary blood vessels and reduce vascular resistance.

The soy flavonoids contained are antispasmodic and also lower blood sugar, and have antipyretic and estrogen-like effects.

Pharmacological Effect of Liquiritigenin.

Licorice has antispasmodic effect on smooth muscle, such as licorice extract, glycyrrhizin, isoglycyrrhizin as well as FM100 can significantly inhibit the motility of the isolated intestinal tubes of animals, and can also relieve intestinal spasms induced by acetylcholine, barium chloride and histamine.

1. It has the functions of antioxidant, anti-ulcer, anti-allergy, anti-mould, preventing skin aging and effectively removing superoxide ion.

2. Glycyrrhizin is a good whitening cosmetic raw material, both can better inhibit tyrosinase activity.

3. It is suitable for sweetening and flavouring of canned food, seasoning, candy, biscuits, candied fruit (Cantonese-style cold fruit).

4. Liquoricein has antispasmodic, treatment of depressive psychosis and other medicinal functions.

Extraction Method of Bulk Liquiritigenin Powder.

(1)Crush liquorice into 60 mesh powder, at 80 ℃, material and liquid mass ratio of 1: 5 ~ 8 conditions, with a concentration of 1 mol / L hydrochloric acid solution extracted for 120 minutes, four layers of gauze filtration, to be filtered, until the filtrate cooled to room temperature, add 1 mol / L of sodium hydroxide solution adjusted to neutral, to get the glycyrrhizin crude extract;

(2) the glycyrrhizin crude extract, on the mixed resin column, with 5-8 times the column volume of deionised water, 5 times the column volume of volume percent concentration of 20% ~ 40% ethanol aqueous solution, 4 times the column volume volume of volume percent concentration of 70% ethanol aqueous solution for the elution, collect the volume percent concentration of 70% ethanol aqueous solution eluent, concentrated under reduced pressure to the sugar level of 30%, add an equal volume of deionised water, stir, and then precipitate at 20 ℃ for 8 days. At 20 ℃ under the condition of precipitation crystal 8 hours, aspirate the supernatant, crystals add 4 times the volume of anhydrous ethanol to dissolve, concentrated under reduced pressure to 30% sugar, add an equal volume of deionized water, stir, at 20 ℃ under the condition of precipitation crystal 8 hours, filtration, the crystals to deionized water to wash to the no alcohol taste, at 60 ℃ under the condition of drying under reduced pressure, that is, to get the purified glycyrrhizin.