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1-deoxynojirimycin Raw Materials 1-deoxynojirimycin powder
Product Overview:
1-Deoxynojirimycin, abbreviated as DNJ, is an alkaloid extracted from the leaves and root bark of Morus alba and also found in other plants and microorganisms. It is an effective α-glucosidase inhibitor with significant hypoglycaemic effect.1-Deoxynojirimycin can inhibit the decomposition of starch and sugar by sucrase, maltase, α-glucosidase, and α-amylase in the body after entering the human body, so as to block the absorption of sugar by the human body, inhibit the rise of blood sugar, and achieve the effect of preventing and controlling diabetes mellitus. It does not cause any change in dietary structure.
1-deoxynojirimycin Raw Materials 1-deoxynojirimycin powder Attributes
CAS:19130-96-2
MF:C6H13NO4
MW:163.17
EINECS:606-239-2
Specification: 99% min Isoliquiritigenin Powder
Sample:1-deoxynojirimycin Powder
Packaging:1kg/bag, 25kg/drum
Brand: Henrikang
Appearance: White
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
1-deoxynojirimycin Raw Materials 1-deoxynojirimycin powder Details
1-deoxynojirimycin Powder Usage and Synthesis.
The biosynthetic pathways of DNJ in Streptomyces, Bacillus and duckweed have been explored and different mechanisms of DNJ synthesis have been found in different species.
Three major synthetic methods of 1-deoxynojirimycin have also been explored, and some of the synthetic DNJ derivatives have been used in clinical applications. In recent years, studies have shown that DNJ (l-deoxynojirimycin), the active ingredient in mulberry leaves, which is only owned by mulberry leaves, hinders the production of glucose from sugar by blocking the action of α-glucosidase, and that mulberry leaf extracts inhibit the intestinal absorption of glucose.
This can inhibit the rise of blood glucose value and blood pressure, have a better inhibition effect on the variability of carcinogens such as benzo(a)pyrene and imidazolopyridine, have anti-cancer effect, at the same time, mulberry leaf extract can also reduce cholesterol, improve liver function and eliminate constipation and so on.
Uses of 1-deoxynojirimycin.
1-Deoxynojirimycin belongs to the potent α-glucosidase inhibitor, absorption is better than acarbose; inhibit the conversion of human body sugar, reduce fasting blood glucose and postprandial blood glucose is better than sulfonylureas, and the possibility of hypoglycemia and other side effects is much lower than that of other blood glucose-lowering drugs, the safety is good; the use of the product can be used without changing the normal dietary structure.
Pharmacological Effect of 1-deoxynojirimycin.
This product belongs to the potent α-glucosidase inhibitor, absorption is better than Acarbose; inhibit the conversion of human body sugar, reduce fasting glucose and postprandial glucose elevation is better than sulfonylureas, and the possibility of hypoglycemia and other side effects is much lower than that of other hypoglycemic drugs, safety is good; the use of this product can be used without changing the normal structure of the diet.
In vitro studies of Bulk 1-deoxynojirimycin Powder.