Pharmaceutical
Human APIs Powder
- Respiratory Drugs Raw Material
- Antiviral Antibacterial
- Antipyretic Analgesics
- Antihistamine Drugs
- Antineoplastic
- Cosmetic Raw Material
OEM & ODM
Veterinary raw materials
Phone: 86-29-89601602
E-mail: sales28@interlgroup.com
Add: Fengcheng 2nd Road, Weiyang District, Xi'an, Shaanxi, China
Gentiopicrin Raw Materials Shikonin powder
Product Overview:
Gentianoside has anti-inflammatory effects, reducing ear swelling in mice and plantar swelling in rats, inhibiting glacial acetic acid-induced increase in peritoneal capillary permeability in mice, and increasing pain threshold. Gentianoside was also found to activate the PI3K/AKT pathway in palmitic acid (PA)-induced HepG2 cells, reducing lipid synthesis and increasing glucose utilisation.
Gentiopicrin Raw Materials Shikonin powder Attributes
CAS:20831-76-9
MF:C16H20O9
MW:356.33
EINECS:244-070-2
Specification: 99% min Gentiopicrin powder
Sample:Gentiopicrin powder
Packaging:1kg/bag, 25kg/drum
Brand: Henrikang
Appearance: White
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
Gentiopicrin Raw Materials Shikonin powder Details
Gentiopicrin powder Usage and Synthesis.
Gentianoside is a common component of traditional Chinese medicine with a variety of pharmacological effects. Studies have shown that gentianoside has anti-inflammatory effects, which can reduce ear swelling in mice and foot-plantar swelling in rats, and inhibit the increase of peritoneal capillary permeability.
In addition, Gentianoside has anti-inflammatory and analgesic effects, which can increase the pain threshold and relieve pain caused by heat and chemical stimuli. In cellular experiments, gentianoside can reduce lipid synthesis and increase glucose utilisation by activating the PI3K/AKT pathway in palmitic acid-induced HepG2 cells.
In addition, gentianoside inhibits the interaction between PAQR3 and P110α and thus activates the PI3K/AKT pathway.
Uses and functions of Gentiopicrin powder.
Gentianoside has antidepressant, hepatoprotective, anti-inflammatory and other effects and efficacy, gentianoside is a kind of cyclic ether terpene glycoside compounds, is the extract of gentian herb, especially in the roots and rhizomes of gentian herb, the content of the substance is relatively high.
1, antidepressant: the occurrence of depression is mainly associated with abnormal cortisol levels, damage to the central nervous system function, etc., and research has found that gentian bittersweet is helpful in reversing the damage of cortisol on the body, so it has a certain effect in alleviating the symptoms of depression, such as depressed state of mind, loss of interest, slow thinking, decreased attention, etc..
2, liver: gentian bittersweet can improve the imbalance of lipid metabolism triggered by long-term alcoholism, but also reduce fat deposition, for alcoholic fatty liver, non-alcoholic fatty liver and so on, have certain effect, but also to prevent mild hepatic fibrosis triggered by hepatic steatosis, is beneficial to the protection of the liver.
3, anti-inflammatory: the substance is also helpful in reducing allergic asthma, osteoarthritis, gastritis and other discomforts, with certain anti-inflammatory effects.
In addition, gentian bittersweet is also helpful in improving diabetes, osteoporosis, etc. It can also increase bile secretion, promote gallbladder contraction, and has an excitatory effect on the central nervous system, etc.. However, the substance is not widely used in the clinic, and the specific mechanism of action needs to be further studied.
Pharmacological Effect of Gentiopicrin powder.
Product method of Bulk Gentiopicrin powder.