Cytidine Diphosphate Choline Raw Materials powder

CAS:987-78-0

MF:C14H26N4O11P2

MW:488.33

EINECS:213-580-7

Specification​: 99% min Cytidine Diphosphate Choline powder

Sample:Cytidine Diphosphate Choline powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Cytidine Diphosphate Choline powder Usage and Synthesis.

It is mainly used for metabolic disorders after craniocerebral trauma and brain surgery, consciousness disorders, tremor paralysis, neurological deafness and tinnitus, as well as sleeping drug poisoning. It also has good effect on Parkinson's syndrome and cerebral thrombosis hemiplegia.

Cytarabine is a mononucleotide composed of nucleic acid, cytarabine, pyrophosphate and choline, which is mainly used for the treatment of various neurodegenerative diseases, such as Alzheimer's disease, multiple sclerosis, amyotrophic lateral sclerosis and so on.

Some studies have also shown that cytarabine can increase the brain's uptake of dopamine and glutamate, thereby improving cognitive performance.

Cytarabine also reduces the release of free fatty acids and restores the activity of mitochondrial ATPase and cell membrane Na+/K+ ATPase, thereby alleviating brain damage.

However, the pathophysiologic mechanisms of neurodegenerative diseases are complex and involve cholinergic deficiencies, glutamate excitotoxicity, neuroinflammation, immune dysregulation, decreased glucose metabolism, and disruption of the blood-brain barrier.

Uses and functions of Cytidine Diphosphate Choline powder.

The product is a precursor of lecithin biosynthesis and induces lecithin biosynthesis. The product can promote the recovery and awakening of brain function. It is suitable for the consciousness disorder of traumatic brain injury, post-stroke, etc. It is also used for the consciousness disorder caused by acute injury of central nervous system.

It is used for consciousness disorder after acute craniocerebral trauma and brain surgery. Cerebral thrombosis, multiple cerebral embolism, tremor paralysis, post-stroke sequelae, insufficient cerebral blood supply due to cerebral arteriosclerosis, hypnotic drugs and carbon monoxide poisoning and various organic encephalopathies.

Preparation of Cytidine Diphosphate Choline powder.

There are more methods for the preparation of sodium cytophosphorylcholine, mainly in three ways. One is microbial fermentation method. This method has problems such as low product concentration and unstable yield. One is organic chemical synthesis method. This method has the problems of difficult to separate the product from the condensate, unsuitable for medicinal use, low reaction conversion rate, many by-products, high cost, serious environmental pollution and so on.

There is also an enzymatic synthesis method, such as the use of microorganisms such as brewer's yeast mud for biosynthesis. Enzymatic synthesis using free brewer's yeast mud cells, simple process, high conversion rate, low cost. The production process of synthesizing sodium cytosine by enzymatic synthesis can be divided into two major parts: enzymatic synthesis process and extraction and purification process.

Product Method of Bulk Cytidine Diphosphate Choline powder.

It can be extracted from liver or yeast, or chemically synthesized. Synthesis is achieved by reacting cytosine-5'-diphosphate with ethyleneimine to form cytosine-5'-diphosphate aminoethyl ester, which is then methylated with iodomethane. It can also be obtained by direct condensation of cytosine-5'-phosphate amide with choline phosphate.