Pyridoxal 5-phosphate Monohydrate Raw materials Powder

CAS:41468-25-1

MF:C8H12NO7P

MW:265.16

EINECS:609-929-1

Specification: 99% min Pyridoxal 5-phosphate Monohydrate Powder

Sample:Pyridoxal 5-phosphate Monohydrate Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:Light Yellow

Storage: Store at -20°C

Shelf Life: 2 Years

Test Method: HPLC

Pyridoxal 5-phosphate Monohydrate Powder Usage and Synthesis.

PLP is so important that it is involved in more than 140 PLP-dependent enzymes, accounting for about 4% of all classified activities.The versatility of PLP comes from its electrophilicity: PLP covalently binds to the substrate at the beginning of the reaction through the formation of an external aldimine, and different types of carbon-negative reactive intermediates can then be stabilized by PLP through a resonance effect.

This function of PLP is also known as "electron trapping". In addition to the electron-trapping effect, acidic and basic groups assisting in proton transfer are equally important, since almost all PLP-dependent reactions generate cationic and anionic intermediates.

Pyridoxal 5-phosphate is an organic synthesis and pharmaceutical intermediate used as a biochemical reagent in laboratory organic synthesis processes and in chemical and pharmaceutical research and development.

Uses of Pyridoxal 5-phosphate Monohydrate.

Pyridoxal 5'-phosphate monohydrate is an endogenous metabolite used as a quantitative tracer during drug development.

Deuteration of this compound has the potential to affect the pharmacokinetic and metabolic profile of the drug. Shukeng Pharma offers a wide range of biochemical reagent products including small molecule and peptide inhibitors, activators and antagonists, natural products, screening compound libraries, modification of peptides, optimization of peptide drugs, and synthesis of small molecule drugs.

Pyridoxal phosphate monohydrate is also used as a chemical intermediate with the molecular formula C8H8NO6P and molecular weight 245.1271.

Pyridoxal phosphate monohydrate is also used in antimalarial drugs, such as piperaquine, whose mechanism of action is to affect the ultrastructure of Plasmodium berghei intra-erythrocytic stage schizonts, which can mainly make the trophozoite food vesicle membranes and mitochondria swollen. The morphology of malaria pigments is variable, and rapid liquid chromatography with fluorescence spectrophotometry can be used to determine the content of piperaquine.

Characteristic of Pyridoxal 5-phosphate Monohydrate.

Product Method of Bulk Pyridoxal 5-phosphate Monohydrate Powder.