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nad Raw Materials Powder β-Nicotinamide adenine dinucleotide
Product Overview:
β-Nicotinamide adenine dinucleotide is used as a coenzyme in redox reactions, as a donor of the ADP-ribose moiety in ADP-ribosylation reactions, and as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide adenine dinucleotide also serves as a substrate for bacterial DNA ligase and a group of enzymes called sirtuins, which use NAD+ to remove acetyl groups from proteins.
nad Raw Materials Powder β-Nicotinamide adenine dinucleotide Attributes
CAS:53-84-9
MF:C21H27N7O14P2
MW:663.43
EINECS:200-184-4
Specification: 99% min nad Powder
Sample:nad
Packaging:1kg/bag, 25kg/drum
Brand: Raw Materials
Appearance:white
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
nad Raw Materials Powder β-Nicotinamide adenine dinucleotide Details
nad Powder Usage and Synthesis.
NAD+ (nicotinamide adenine dinucleotide, NAD+ for short) can effectively protect kidney damage caused by renal ischemia, and NAD+ has important application value in the preparation of drugs for the prevention and treatment of renal ischemic damage.
In addition, nicotinamide adenine dinucleotide has certain applications in the preparation of drugs for the treatment of inflammatory pain. NAD+ participates in regulating formalin and complete Freund's adjuvant (CFA)-induced inflammatory pain through NAD+-dependent deacetylases SIRT1 and SIRT2, while SIRT1 and SIRT2 participate in the inhibitory effect of NAD+ on inflammatory pain through different mechanisms, thereby achieving analgesic effect on inflammatory pain.
Uses and functions of nad.
Nicotinamide adenine dinucleotide is a coenzyme drug. It is mainly used in clinical practice for the adjuvant treatment of coronary heart disease and can improve symptoms such as chest tightness and angina pectoris. Adverse reactions occasionally include dry mouth, dizziness, nausea, etc.
It is an essential coenzyme in organisms and is used in biochemical research, clinical diagnosis, clinical drugs and drug research.
Preparation of nad.
Product method of Bulk nad Powder.
Extraction from fresh yeast, the steps are as follows: fresh pressed yeast [crushing, extraction] extract [separation] filtrate [primary adsorption] [elution] primary eluate [neutralization] [secondary adsorption] [elution] [third adsorption] [elution] third eluate [precipitation] [filtration] [drying] coenzyme I