Betulinic Acid raw Materials Powder in Manufacturer price

CAS: 472-15-1

MF: C30H48O3

MW: 456.71

EINECS: 207-448-8

Specification​: 99% min Betulinic Acid Powder

Sample: Betulinic Acid Powder Avaliable

Packaging: 1kg/bag, 25kg/drum

Brand: Ausreson

MOQ: 1 kg

Keywords: Betulinic Acid Powder

Appearance: white powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Last updated: March 2026

Betulinic Acid Powder Usage and Synthesis.

Betulinic acid is a natural product with multiple biological activities, such as anti-inflammatory, antibacterial, anti-malarial and anti-tumor. It has a strong toxic effect on various tumors such as melanoma, neuroectodermal and malignant brain tumors, and has no killing effect on normal cells.

In addition, buy betulinic acid also has a strong inhibitory effect on HIV-1 virus, and its antiviral activity is stronger than some existing clinical drugs. Therefore, betulinic acid has broad application prospects, attracting many companies to enter this field.

• Inducing Selective Apoptosis: Betulinic acid acts directly on the mitochondria of abnormal cells, triggering the release of Cytochrome C. In 2026, this is a cornerstone of "Non-Genotoxic Oncology," as it bypasses $p53$ mutations that often make tumors resistant to standard chemotherapy.

• Anti-Retroviral (HIV) Inhibition: It functions as a Fusion Inhibitor, preventing the HIV virus from entering host cells. In 2026, betulinic acid derivatives are at the forefront of long-acting viral suppression research.

• Potent Tyrosinase Inhibition: In the 2026 luxury skincare market, it is the #1 natural alternative to hydroquinone. It effectively suppresses Melanogenesis, reducing hyperpigmentation and "age spots" without the cellular toxicity of synthetic whiteners.

• Endothelial Anti-Inflammatory Effects: It inhibits the NF-kappa B signaling pathway, making it an excellent 2026 candidate for treating chronic inflammatory skin conditions like psoriasis and severe acne.

Uses of Betulinic Acid.

1. Anti-inflammatory effect

Most pentacyclic triterpenoids have anti-inflammatory activity. The anti-inflammatory effect of betulinic acid has been verified in in vitro and in vivo model systems. It can inhibit the production of PGE2 and reduce inflammatory response.

2. Antibacterial effect

It has a certain antibacterial effect and can inhibit a variety of bacteria including Escherichia coli, Bacillus subtilis, Staphylococcus aureus and Staphylococcus epidermidis.

3. Antiviral effect

Betulinic Acid Price has a relatively prominent antiviral activity, especially anti-HIV activity. It also has effective effects in anti-hepatitis C virus, anti-herpes simplex virus, anti-echovirus, anti-influenza virus, etc.

4. Anti-hyperlipidemic effect

Studies have found that betulinic acid and its derivatives can play an anti-hyperlipidemic effect by regulating adipose factors, reducing lipid production, and reducing triglyceride and total cholesterol levels.

5. Anti-diabetic effect

It has shown good efficacy in the treatment of diabetes, mainly by inhibiting α-amylase and α-glucosidase to reduce the hydrolysis of polysaccharides and promote glycogen synthesis.

Why "98% HPLC Standardized Isolate" is the 2026 Quality Standard

1. Purity Over Raw Extract: In 2026, "Birch Bark Extract" is no longer enough for clinical results. Premium Betulinic Acid Powder must be $\geq$ 98% pure (HPLC) to ensure the specific triterpenoid ratios required for mitochondrial targeting.

2. Solubility Enhancement: Naturally, betulinic acid has poor water solubility. 2026's gold-standard powders are often Micronized or prepared for Cyclodextrin Complexation, significantly increasing their bioavailability in oral and topical formulations.

3. Sustainable Bark Sourcing: 2026 "Eco-Pharma" standards require that the acid be sourced from the waste bark of the timber industry, ensuring a zero-deforestation footprint for global supply chains.

FAQ.

No. In 2026, we clarify: Betulin is the precursor found in higher quantities in birch bark. Betulinic Acid is the oxidized, more biologically active form. While both are beneficial, the acid form is what possesses the potent anti-tumor and anti-viral properties.

Yes. In 2026, it is a key ingredient in "Clinical Brightening" serums. It not only lightens dark spots but also provides an anti-aging effect by inhibiting the enzymes that break down collagen (collagenase).

Betulinic acid derivatives are being developed as Maturation Inhibitors, a new class of drugs that prevent the virus from becoming infectious, providing a crucial backup for patients who have developed resistance to traditional NRTIs.

For topical applications, concentrations of 0.5% to 1.0% are standard. For oral research protocols, dosages typically range from 100mg to 500mg daily, often formulated with lipid carriers.

Product Method of Bulk Betulinic Acid Powder.

First, it is extracted and separated from natural plants. This method consumes a lot of solvents, has a low yield, and impurities are difficult to separate, so it is rarely used;

Second, betulin is used as a precursor to obtain betulinic acid through organic synthesis. This method has been applied to industrial production and can obtain industrial-scale betulinic acid, which is the main source of betulinic acid on the market;

Third, betulinic acid is generated through microbial transformation using betulin as a precursor. This method represents a new direction for the future plant extraction industry, but there are still many technical problems that have not been solved.

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