Betulinic Acid raw Materials Powder

CAS:472-15-1

MF:C30H48O3

MW:456.71

EINECS:207-448-8

Specification​: 99% min Betulinic Acid Powder

Sample:Betulinic Acid Powder

Packaging:1kg/bag, 25kg/drum

Brand: raw Materials

Appearance:white

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Betulinic Acid Powder Usage and Synthesis.

Betulinic acid is a natural product with multiple biological activities, such as anti-inflammatory, antibacterial, anti-malarial and anti-tumor. It has a strong toxic effect on various tumors such as melanoma, neuroectodermal and malignant brain tumors, and has no killing effect on normal cells.

In addition, betulinic acid also has a strong inhibitory effect on HIV-1 virus, and its antiviral activity is stronger than some existing clinical drugs. Therefore, betulinic acid has broad application prospects, attracting many companies to enter this field.

Uses of Betulinic Acid.

1. Anti-inflammatory effect

Most pentacyclic triterpenoids have anti-inflammatory activity. The anti-inflammatory effect of betulinic acid has been verified in in vitro and in vivo model systems. It can inhibit the production of PGE2 and reduce inflammatory response.

2. Antibacterial effect

It has a certain antibacterial effect and can inhibit a variety of bacteria including Escherichia coli, Bacillus subtilis, Staphylococcus aureus and Staphylococcus epidermidis.

3. Antiviral effect

It has a relatively prominent antiviral activity, especially anti-HIV activity. It also has effective effects in anti-hepatitis C virus, anti-herpes simplex virus, anti-echovirus, anti-influenza virus, etc.

4. Anti-hyperlipidemic effect

Studies have found that betulinic acid and its derivatives can play an anti-hyperlipidemic effect by regulating adipose factors, reducing lipid production, and reducing triglyceride and total cholesterol levels.

5. Anti-diabetic effect

It has shown good efficacy in the treatment of diabetes, mainly by inhibiting α-amylase and α-glucosidase to reduce the hydrolysis of polysaccharides and promote glycogen synthesis.

Pharmacological effect of Betulinic Acid.

Product Method of Bulk Betulinic Acid Powder.

First, it is extracted and separated from natural plants. This method consumes a lot of solvents, has a low yield, and impurities are difficult to separate, so it is rarely used;

Second, betulin is used as a precursor to obtain betulinic acid through organic synthesis. This method has been applied to industrial production and can obtain industrial-scale betulinic acid, which is the main source of betulinic acid on the market;

Third, betulinic acid is generated through microbial transformation using betulin as a precursor. This method represents a new direction for the future plant extraction industry, but there are still many technical problems that have not been solved.