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Natural Levomefolate calcium raw Materials Powder
Product Overview:
Levomefolate calcium is the calcium salt of l-5-methyltetrahydrofolate, which belongs to the folate family of vitamins (Vitamin B9, Folic Acid), which is a coenzyme form of folic acid. l-5-methyltetrahydrofolate calcium (5-mthf), is the salt-forming methyl derivative form of folic acid that is naturally occurring, and 5-mthf is also known as levomethylfolate, which is the most biologically active and functional form of folic acid, and is much more readily absorbed than regular folic acid.
Natural Levomefolate calcium raw Materials Powder Attributes
CAS:151533-22-1
MF:C20H27CaN7O6
MW:501.56
EINECS:691-636-3
Specification: 99% min Levomefolate calcium Powder
Sample:Levomefolate calcium Powder
Packaging:1kg/bag, 25kg/drum
Brand: raw Materials
Appearance:white
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
Natural Levomefolate calcium raw Materials Powder Details
Levomefolate calcium Powder Usage and Synthesis.
Folic acid deficiency reduces the ability of cells to synthesise and repair DNA and supplementation may be a more favourable approach Increased folic acid reduces homocysteine levels and supports normal cell proliferation, vascular endothelial function . Cardiovascular disease, neurological function, and especially during pregnancy supplementation with 5-MTHF has been shown to reduce the risk of developing neural tube malformations and recurrences.
Uses of Levomefolate calcium.
The biochemical pathway to bioactive folate involves a series of enzymatic reactions and cofactors. Absorbed folate is reduced and methylated to 5-MTHF during metabolism in intestinal mucosal cells.
This transformation is limited and does not alter the appearance of folate in the blood circulation, where the bisacodylate is subsequently converted to s-adenosylmethionine (SAMe), a methyl donor involved in a number of biochemical processes. It also serves as a donor for nucleotide synthesis and supports biosynthesis of DNA.
Metabolic pathway of Levomefolate calcium.
The two main metabolic pathways in which ordinary folic acid must be converted to l-type methylfolate in order to participate: the methylation process and dna synthesis, the only form of free folic acid normally present in human plasma and cells is 5-mthf.
Deficiency of folic acid is usually due to vitamin deficiencies resulting in insufficient absorption, an increased need for folic acid during pregnancy and breastfeeding, child growth, and the need to give supplements when the consumption of folic acid-rich foods does not guarantee the dosage supplied under the influence of altered absorption or metabolism, or of pharmaceuticals.
Product Method of Bulk Levomefolate calcium Powder.