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Supply telmisartan Raw Materials powder telmisartan
Product Overview:
Telmisartan is a novel antihypertensive drug, a specific angiotensin II receptor (ATⅠ) antagonist, used to treat essential hypertension. Alternative angiotensin II receptors bind with high affinity to ATⅠ receptor subtypes (known angiotensin II action sites). Telmisartan does not have any site agonist effect AT the ATⅰ receptor site, and selectively binds to the ATⅰ receptor, and the binding effect is long-lasting.
Supply telmisartan Raw Materials powder telmisartan Attributes
CAS:144701-48-4
MF:C33H30N4O2
MW:514.62
EINECS:620-494-7
Specification: 99% min telmisartan
Sample:telmisartan powder
Packaging:1kg/bag, 25kg/drum
From: Raw Materials
Appearance:white
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
Supply telmisartan Raw Materials powder telmisartan Details
telmisartan of Usage and Synthesis.
1. Treat high blood pressure. Telmisartan is an angiotensin II receptor antagonist and can be used in the treatment of adult hypertension.
2. Reduce the incidence of cardiovascular and cerebrovascular diseases. Telmisartan is suitable for patients with cardiovascular and cerebrovascular disease risk factors such as renal insufficiency and diabetes. It can effectively reduce the incidence of myocardial infarction, cerebral thrombosis, cerebral hemorrhage and other diseases.
Telmisartan must be taken on time and according to the doctor's advice, hypertension should be monitored on time during the medication, and the dosage should be adjusted according to the doctor's advice. At the same time, liver and kidney function and electrolyte should be regularly reviewed.
Uses of telmisartan.
Telmisartan is an orally active, specific angiotensin | receptor (AT type) antagonist. This product can selectively bind to the AT1 receptor, and the action time is long, can increase the level of angiotensin I.
It is used primarily to lower blood pressure, but also to reduce the risk of myocardial infarction, stroke, or death from cardiovascular disease in patients (age 55 years and older) who are at high risk of serious cardiovascular events and cannot be treated with angiotensin converting enzyme (ACE) inhibitors.
Telmisartan can reduce aldosterone levels, but does not inhibit human plasma renin activity or block ion channels, and does not inhibit angiotensin-converting enzyme (ACE, kinin), so the administration of telmisartan does not enhance bradykinin-mediated adverse reactions.
Pharmacological action of telmisartan.
Product method of Bulk telmisartan Powder.