Supply Mangiferin Raw Materials powder

CAS:4773-96-0

MF:C19H18O11

MW:422.34

EINECS:624-757-7

Specification: 99% min Mangiferin

Sample:Mangiferin powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:Yellow

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Mangiferin of Usage and Synthesis.

1. Used in the treatment of upper respiratory tract infection;

2. Mango cough suppressant can be made, with good cough suppressant and anti-infection effect;

3. Mangiferin with erythromycin can prevent and control acne;

4. Mangiferin synergises with oxaliplatin, which can promote cancer cell apoptosis and improve the in vitro anticancer activity of oxaliplatin.

Uses of Mangiferin.

Mangiferin has central nervous system inhibition, anti-inflammatory, anti-bacterial, anti-herpes simplex virus, choleretic and immune effects, and protective effects on simulated plateau acute hypoxic liver injury. Pharmacological experiments show that it is used in the treatment of chronic bronchitis with good efficacy, is the main active ingredient in the treatment of hepatitis with Tibetan yin chen, and is the anti-viral active ingredient in the rhizome of Zhi Mu. A natural phenolic flavonoid that can be studied as an anti-microbial or anti-diabetic drug with anti-inflammatory and antioxidant activity. Mangiferin can be used to help identify and characterise type II 5-alpha-reductase.MGF can be used as a reference substance for flavonoid analysis.MGF may act as a facilitator of gastrointestinal transit (GIT).

Pharmacological action of Mangiferin.

1.Antioxidant effect due to the special structure of mangiferin, the molecule has a number of phenolic hydroxyl, and phenolic hydroxyl happens to be an important group for scavenging free radicals and reactive oxygen species. The mechanism of its action on free radicals can be attributed to two aspects: on the one hand, it acts directly on the removal of free radicals, and on the other hand, it acts on iron and copper ions to reduce their further reaction with free radicals.

2.Anti-tumour effect: The occurrence of leukaemia is related to the disturbance of cell cycle regulation, and there is a close relationship between cell cycle regulation and telomerase activity. Therefore, the study of telomerase and cell cycle regulation abnormality has become a new direction to explore the occurrence and treatment of leukaemia. The development of leukaemia is associated with cell cycle regulation disorders, and there is a close relationship between cell cycle regulation and the expression of telomerase activity. Therefore, the study of telomerase and cell cycle regulation abnormality has become a new direction to explore the occurrence and treatment of leukaemia.

3.Neuroprotective effect: Mangiferin with polyphenolic structure protects neurons by reducing glutamate-induced cell death in neurons through attenuating Ca2+ in-flow and oxidative stress.

4. Antiviral effect has an in vitro anti-herpes simplex virus type I (HSV-I) effect, the reduction rate of empty spots is 56.8%, and its antiviral effect is attributed to its ability to inhibit intracellular viral replication.

5. Antipyretic effect on endotoxin-induced fever in experimental animal models have good antipyretic effect, and positive correlation with the dose, and has a good protective effect on thermal injury.

6. Analgesic effect has significant analgesic effect on acetic acid-induced and hot plate test-induced pain. By comparing with naloxone hydrochloride, it is found that mangiferin-induced nociceptive deficit is not dependent on opioid receptors, and its analgesic effect is significant with slight effect on peripheral nerves.

Product method of Bulk Mangiferin Powder.