manufacturers Betahistine Dihydrochloride raw Materials powder

CAS:5579-84-0

MF:C8H14Cl2N2

MW:209.12

EINECS:226-966-5

Specification​: 99% min Betahistine Dihydrochloride Powder

Sample:Betahistine Dihydrochloride Powder Avaliable

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

MOQ:1 KG

Appearance:yellow powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

What is Betahistine Dihydrochloride Powder?

Betahistine Dihydrochloride Powder is the pure, active pharmaceutical ingredient (API) form of Betahistine, a histamine-like molecule. It is not a dietary supplement but a pharmaceutical compound primarily used to manage symptoms associated with Meniere's disease, such as:

• Vertigo (a spinning sensation)

• Tinnitus (ringing in the ears)

• Hearing loss (in some cases)

It works by improving blood flow in the inner ear and is believed to act as a partial histamine H1 receptor agonist and an H3 receptor antagonist. This dual action is thought to reduce the pressure and fluid buildup in the inner ear, thereby alleviating the frequency and severity of vertigo attacks.

Betahistine Dihydrochloride Powder Usage and Synthesis.

Betahistine hydrochloride is mainly used for Meniere's syndrome, vascular headache and cerebral arteriosclerosis, and can be used to treat acute ischemic cerebrovascular diseases, such as cerebral thrombosis, cerebral embolism, transient cerebral insufficiency, etc. It is also effective for orthostatic vertigo and tinnitus caused by hypertension.

Uses of Betahistine Dihydrochloride.

Betahistine hydrochloride has the effect of dilating blood vessels and increasing blood flow. It can be used to treat cardiovascular and cerebrovascular diseases, for the treatment of Meniere syndrome, cerebral arteriosclerosis and vascular headache, and can also be used to treat cerebral insufficiency of blood supply, cerebral embolism and cerebral thrombosis and other diseases. In addition, it has a good effect on eliminating lymphadendema and reducing arterial pressure, and can also be used to improve dizziness and tinnitus symptoms.

Pharmacological action of Betahistine Dihydrochloride.

Betahistine hydrochloride has a significant dilating effect on cerebrovascular and cardiovascular systems, especially on the vertebral base artery system, which significantly increases the blood flow of the heart, brain and surrounding circulation, improves blood circulation, and reduces systemic blood pressure. In addition, it can increase the blood flow of the cochlea and vestibule, thereby eliminating internal ear vertigo, tinnitus and ear closure, increase capillary permeability, and promote extracellular fluid absorption. Elimination of lymphoid edema; It can counter the vasoconstriction effect of catecholamines and reduce arterial pressure, inhibit plasma coagulation and ADP-induced platelet agglutination, prolong the time of thrombosis in vitro in rats, and have slight diuretic effect.

Important Considerations for Use and Sourcing

It is imperative to understand that Betahistine Dihydrochloride is a potent pharmaceutical ingredient.

• Not a Dietary Supplement: In many countries, including the United States, Betahistine is not approved as a dietary supplement. It is a prescription drug in most European countries, Canada, and many other regions.

• Purity and Sourcing are Paramount: For pharmaceutical compounding or research purposes, sourcing high-purity Betahistine HCl from a reputable and certified supplier is non-negotiable. The product must meet strict pharmacopeial standards (like USP or EP) for identity, purity, and strength.

• Dosage is Highly Individualized: Therapeutic dosage must be determined by a qualified healthcare professional. Self-medicating with raw powder is extremely dangerous due to the risk of incorrect dosing and potential side effects.