Cyanoacetic Acid Raw Material Powder

CAS: 372-09-8

MF: C3H3NO2

MW: 85.06

EINECS: 206-743-9

Specification​: 99% min Cyanoacetic Acid

Sample: Cyanoacetic Acid Powder

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Portal:https://henrikang.en.made-in-china.com/

Cyanoacetic Acid Powder Usage and Synthesis.

Cyanoacetic Acid Powder is an important class of organic synthesis raw materials and intermediates of pharmaceuticals and dyestuffs, Cyanoacetic Acid CAS 372-09-8 is used in the manufacture of adhesives, vitamins, etc. 

Its derivatives methyl cyanoacetate, ethyl cyanoacetate, etc. have important uses in medicine, agriculture, new materials, etc. Therefore, the demand for high purity cyanoacetic acid The demand for high purity cyanoacetic acid is increasing. 

Cyanoacetic Acid Raw Material is also used in the synthesis of the pesticide cyanuric acid. 

Cyanoacetic Acid Raw Material is an important intermediate in the production of pharmaceuticals, dyestuffs and pesticides, and is mainly used in the synthesis of cyanoacetic acid esters.

Uses and functions of Cyanoacetic Acid Powder.

Cyanoacetic Acid Powder is used in the pharmaceutical industry for the production of vitamin B6, carfentine, medical adhesives, etc. It is also used in the synthesis of the pesticide fenitrothion. Cyanoacetic acid is an intermediate of the fungicides rice fungicide and fenitrothion, and is an intermediate of the pharmaceutical caffeine. Application 

Cyanoacetic Acid Powder is white crystal with hygroscopicity. Soluble in water, ethanol and ether, slightly soluble in benzene and chloroform.

Organic synthesis intermediates, Cyanoacetic Acid Powder is mainly used in the synthesis of cyanoacetic esters, also used in the production of methyl and n-butyl alpha cyanoacrylate (medical adhesives), vitamin B6, caffeine, barbiturates, etc..

It is an important intermediate in the production of medicine, dyestuff and pesticide, mainly used in the synthesis of cyanoacetate esters, Cyanoacetic Acid Powder is also used in the production of methyl α-cyanoacrylate and n-butyl ester (medical adhesive), the pharmaceutical industry for the production of vitamin B6, carfentine, barbiturates, etc.. It is also a large amount of raw material for the production of pesticide fungicide cymoxanil.

Pharmacological Effects of Cyanoacetic Acid Powder.

Production method of Cyanoacetic Acid Powder

A method for the preparation of Cyanoacetic Acid Powder, characterized in that it comprises the steps of:

• (1) cyanidation reaction: carrying out a cyanidation reaction between sodium chloroacetate and sodium cyanide to produce an aqueous solution of sodium cyanoacetate;
• (2) Acidification reaction: in step
• (2) acidification reaction: adding hydrochloric acid to the aqueous sodium cyanoacetate solution described in step (1) for acidification to obtain a mixed solution of cyanoacetic acid and sodium chloride
• (3) Dehydration under reduced pressure: dehydration of the solution of cyanoacetic acid and sodium chloride as described in step (2) under negative pressure.
• (3) dehydration under reduced pressure: evaporating and dehydrating said mixed solution of cyanoacetic acid and said sodium chloride in step (2) under negative pressure, precipitating said sodium chloride and filtering said sodium chloride;
• (4) Melt crystallization: using a crystallizer, preheating said crystallizer so that said cyanoacetic acid of step

(3) of said cyanoacetic acid in a molten state, cooling said cyanoacetic acid in a molten state at a rate of 10°C to 20°C/h to the crystallization temperature of said cyanoacetic acid, so that said cyanoacetic acid crystallizes; separating the crystallized product solid-liquid, using the solid phase product therein as raw material and recovering the residual liquid; then heating said crystallizer to 40-45°C at a rate of 2°C to 6°C/h, holding the heat, so that said solid phase product is partially The uncrystallized mother liquor is used as raw material for melting and crystallizing again; the crystals obtained by placing in said crystallizer are heated up to full melting, and the cyanoacetic acid crystals are finally obtained.

The advantages of this method are: through the process of cyanidation, acidification, decompression dehydration and crystallization, the purity of cyanoacetic acid is effectively improved, and no solvent needs to be added during the melt crystallization purification process, which avoids the pollution of the product by the solvent, and reduces the solvent recovery process and saves the equipment investment, and the purity of the purified product is high and the yield is high, with the product purity reaching 99% and the yield reaching 90%.