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  • Ketoconazole Raw Materials Powder

    • Ketoconazole Raw Materials Powder
    • Ketoconazole Raw Materials Powder
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    Product Overview:

    Factory Supply Purity 99% Ketoconazole Raw Material, High Quality Supply Ketoconazole Powder Factory Supply Supply Ketoconazole Powder, Manufacturer of Supply Ketoconazole Raw Materials. Ketoconazole Raw Powder is an imidazole broad-spectrum antifungal drug, an antifungal agent used to treat conditions such as foot odour and excessive dandruff.

    Ketoconazole Raw Materials Powder Attributes

    Ketoconazole Raw Materials Powder CAS  65277-42-1 Pharmaceutical API Factory Supply

    CAS: 65277-42-1

    MF: C26H28Cl2N4O4

    Ketoconazole

    MW: 531.43

    EINECS:  265-667-4

    Specification​: 99% min Ketoconazole 

    Sample: Ketoconazole Powder

    Packaging:1kg/bag, 25kg/drum

    Brand: Henrikang

    Appearance: White Powder

    Storage: Cool Dry Place

    Shelf Life: 2 Years

    Test Method: HPLC

    Portal:https://henrikang.en.made-in-china.com/

    Ketoconazole Raw Materials Powder Details

    Ketoconazole Powder Usage and Synthesis.

    Ketoconazole Powder is an imidazole-based broad-spectrum antifungal agent, marketed under the trade names Gold Dakinin, Mycoconazole and Konazole, which inhibits ergosterol biosynthesis in fungal cell membranes by highly selectively interfering with the activity of fungal cytochrome P-450. 

    An antifungal, Ketoconazole Raw Materials is used to treat conditions such as foot odour and excessive dandruff. Skin fungal diseases, lichen planus and ringworm caused by skin fungi and yeasts can be treated with Ketoconazole CAS 65277-42-1 when topical treatment or oral ashwagandha is ineffective, or for severe recalcitrant skin fungal infections difficult to receive ashwagandha treatment.

    Ketoconazole Powder

    Uses and functions of Ketoconazole Powder.

    Ketoconazole lotion, as a topical skin medication, is used clinically for the treatment and prevention of a variety of infections caused by Malassezia, such as lichen planus, seborrheic dermatitis, and scalp chafing (dandruff), and for the rapid relief of flaking and itching caused by seborrheic dermatitis and scalp chafing.

    Ketoconazole Powder

    Ketoconazole is indicated for the treatment of the following systemic fungal infections:

    • 1. candidiasis, chronic cutaneous mucosal candidiasis, oral candida infections, urinary tract candida infections, chronic, recurrent vaginal candidiasis for which topical therapy is ineffective.
    • 2. Dermatophytosis.
    • 3. Coccidioidomycosis.
    • 4. Histoplasmosis.
    • 5. Colouring fungal disease.
    • 6. Coccidioidomycosis parapsilosis. Skin fungal diseases, lichen planus and ringworm caused by skin fungi and yeasts can be treated with this product when topical treatment or oral ashwagandha is ineffective, or when it is difficult to accept ashwagandha treatment for severe and persistent skin fungal infections.
    • Ketoconazole Powder

    Pharmacological Effects of Ketoconazole Powder.

    1.Pharmacology ketoconazole belongs to the pyrrole class antifungal drugs, on the deep infection of fungi such as Candida, colouring fungi, Coccidioides, histoplasmosis, sporotrichum, etc. are antibacterial, on Trichophyton mentagrophytes, etc. also have antibacterial activity. The product has weaker effect on Aspergillus, Schenk's sporotrichum, some dark spore family, Trichoderma spp.

    This product by interfering with the activity of cytochrome P-450, thus inhibiting the biosynthesis of ergosterol, the main sterol of fungal cell membrane, damage to the fungal cell membrane and change its permeability, so that important intracellular material leakage.

    Ketoconazole can inhibit the biosynthesis of triacylglycerol and phospholipids in fungi, inhibit the activity of oxidase and peroxidase, and cause intracellular hydrogen peroxide accumulation leading to cellular submicroscopic degeneration and cell necrosis. In the case of Candida albicans, it can inhibit the process of transformation from budding to invasive hyphae.

    Production method of Ketoconazole Powder.

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