Pharmaceutical Bulk Furacilin Powder

CAS:59-87-0

MF: C6H6N4O4

MW: 198.14

EINECS: 200-443-1

Specification​: 99% min Furacilin Powder

Sample: Furacilin Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Furacilin Powder Usage and Synthesis.

Furacilin is a synthetic nitrofuran topical disinfectant that can play a role in interfering with the sugar metabolism process and oxidase system of bacteria, thus achieving the purpose of bacteriostatic or bactericidal.

Furacilin has a wide antibacterial spectrum, resistance to a variety of gram-positive and negative bacteria, in vitro can inhibit general bacteria, higher concentrations can kill bacteria, external rinsing or wet compresses to deal with body surface infections and skin diseases is more effective, and has been vigorously promoted in the clinic.

Furacilin is a yellow crystalline powder, odourless, light taste at first, but there is a slightly bitter aftertaste, the colour darkens under sunlight, 236-240 ℃ melting and decomposition at the same time. Slightly soluble in ethanol, very slightly soluble in water, almost insoluble in ether and chloroform.

Uses and functions of Furacilin.

Furacilin is a nitrofuran antibacterial drug. This group of drugs also includes furazolidone and furotoxin.

Furacilin is highly toxic orally and is used for topical or surface disinfection in surgery.

Nitrofuran antimicrobials, mainly used for poultry, livestock and aquatic fish disease prevention, antibacterial.

Pharmacological Effects of Bulk Furacilin Powder.

Furacilin affects a wide range of positive and negative bacteria, and a 1:100,000 to 1:200,000 solution is bacteriostatic for most bacteria, while the bactericidal concentration is about twice as high as the bacteriostatic concentration.

But for some strains of bacteria, even if greatly exceeded the above concentration is not sensitive.

For example, the effectiveness is poor for Mycobacterium avium, Mycobacterium avium, Mycobacterium tuberculosis and Mycobacterium diphtheriae, and even worse for Pseudomonas aeruginosa.

Production method of Bulk Furacilin .

5-Nitrofurfural is produced from furfural by nitration, esterification and hydrolysis, and then furacilin is produced by aminocondensation with hydrochloric acid.