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L-5-MTHF Ca Raw Materials Powder
Product Overview:
L-5-MTHF Ca is the calcium salt of L-5-methyltetrahydrofolate, which belongs to the folate family of vitamins (vitamin B9, folic acid), and which is a coenzyme form of folic acid. l-5-Methyltetrahydrofolate calcium (5-mthf), the naturally occurring salt-forming methyl derivative form of folic acid, and 5-mthf, also known as levomethylfolate, are the most biologically active and functional forms of folic acid, and are more easily absorbed than regular It is the most biologically active and functional form of folic acid and is more easily absorbed than ordinary folic acid.
L-5-MTHF Ca Raw Materials Powder Attributes
CAS:151533-22-1
MF: C20H27CaN7O6
MW: 501.56
EINECS:691-636-3
Specification: 99% min L-5-MTHF Ca Powder
Sample: L-5-MTHF Ca Powder
Packaging:1kg/bag, 25kg/drum
Brand: Henrikang
Appearance: White Powder
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
L-5-MTHF Ca Raw Materials Powder Details
L-5-MTHF Ca Powder Usage and Synthesis.
L-5-MTHF Ca is present in the blood and tissues of the human body mainly in the form of L-5-MTHF and is involved in many biochemical reactions in the human body. L-5-MTHF is the main form of folate that plays a role in the body, and it can be directly absorbed and utilized by the human body without complicated enzymatic reaction. Folic acid is mainly absorbed by the upper part of the small intestine.
Uses and functions of L-5-MTHF Ca.
L-5-MTHF Ca deficiency reduces the ability of cells to synthesise and repair DNA and supplementation may be a more favourable approach Increased folic acid reduces homocysteine levels and supports normal cell proliferation, vascular endothelial function . Cardiovascular disease, neurological function, and especially during pregnancy supplementation with 5-MTHF has been shown to reduce the risk of developing neural tube malformations and recurrences.
The biochemical pathway of bioactive folate involves a series of enzymatic reactions and cofactors. Absorbed folic acid is reduced and methylated to 5-MTHF during metabolism in intestinal mucosal cells.
This transformation is limited and does not alter the appearance of folic acid in the circulation, and the bisacodylate is subsequently converted to s-adenosylmethionine (SAMe), a methyl donor involved in a number of biochemical processes. It also serves as a donor for nucleotide synthesis and supports biosynthesis of DNA.
Pharmacological Effects of L-5-MTHF Ca Raw Materials .
Functional Deficiency of folic acid reduces the ability of cells to synthesise and repair DNA, and supplementation may be a more favourable way to Increased folic acid reduces homocysteine levels and supports normal cell proliferation, vascular endothelial function . Cardiovascular disease, neurological function, and especially 5-MTHF supplementation during pregnancy has been shown to reduce the risk of developing neural tube malformations and recurrence.
Metabolic pathwaysThe two main metabolic pathways in which ordinary folic acid must be converted to l-type methylfolate in order to participate: the methylation process and dna synthesis, the only form of free folic acid present in plasma and cells that normally occurs in the body is 5-MTHF.
Deficiency of folic acid is usually due to vitamin deficiencies resulting in insufficient absorption, an increased need for folic acid during pregnancy and lactation, growth of the child, and the need to give supplements when the consumption of folic acid-rich foods does not guarantee the provision of a dose under the influence of altered absorption or metabolism, or medications.
Mechanism of action The biochemical pathway of bioactive folic acid involves a series of enzymatic reactions and cofactors.
Production method of L-5-MTHF Ca Raw Powder .
The two main metabolic pathways in which ordinary folic acid must be converted to l-type methylfolate in order to participate: the methylation process and dna synthesis, the only form of free folic acid normally present in human plasma and cells is 5-mthf.
Deficiency of folic acid is usually due to vitamin deficiencies resulting in insufficient absorption, an increased need for folic acid during pregnancy and breastfeeding, child growth, and the need for supplementation when the consumption of folic acid-rich foods does not guarantee the dosage supplied under the influence of altered absorption or metabolism, or of pharmaceuticals.