Moxonidine Raw Material Moxonidinum Powder

CAS: 75438-57-2

MF: C9H12ClN5O

MW:241.68

EINECS: 629-833-3

Specification​: 99% min Moxonidine 

Sample: Moxonidine Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Moxonidine Raw Materials Usage and Synthesis

Manufactory Supply Moxonidine Raw Powder High Quality Moxonidine Raw Material , High Purity 99% Moxonidine Powder CAS 75438-57-2 Moxonidine Raw Powder. Moxonidine Powder belongs to a new class of antihypertensive drugs commonly used in the treatment of essential hypertension.

Uses and functions of Moxonidine Powder

Moxonidine, also known as Moxonidine, chemically known as 4-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine, is a highly selective imidazoline-type I receptor agonist, which reduces peripheral sympathetic activity by agonising the ventral ventral lateral nucleus of the medulla oblongata (RVLM)-Imidazoline-type I receptor, thus relaxing the vasodilatation and decreasing peripheral resistance to vascular resistance so that the blood pressure decreases, and it belongs to a new type of antihypertensive drug, which is commonly used in the treatment of essential hypertension.

• 1. It works by stimulating central presynaptic α2-receptors. Its antihypertensive effect is similar to that of the calcium antagonist nifedipine and the ACE inhibitor captopril. It is used in essential hypertension.   
• 2. Interferes with renal interstitial fibrosis and thus protects the kidneys.
• 3.Acts by stimulating central presynaptic α2-receptors. Its antihypertensive effect is similar to that of the calcium antagonist nifedipine and the ACE inhibitor captopril. It is used in essential hypertension.

Pharmacological Effects of Moxonidine Raw Powder

• The reaction of 5-amino-4,6-dichloro-2-methylpyrimidine and 1-acetyl-2-imidazolidin-2-one yields moxonidine by the action of the resulting product and sodium methanol.
• Production method of Raw Moxonidine Powder
• Method 1: Reaction of 5-amino-4,6-dichloro-2-methylpyrimidine and 1-acetyl-2-imidazolidin-2-one, the resulting product and sodium methanolate yielded moxonidine.
• Method 2: Reaction of 5-amino-4-chloro-6-methoxy-2-methylpyrimidine with ammonium thiocyanate and benzoyl chloride to give (I). De-benzoylated to give (II), methylated to give (III), and then interacted with ethylenediamine to give moxonidine.