High Quality Genistein Raw Powder

CAS:446-72-0

MF:C15H10O5

MW:270.24

EINECS:207-174-9    

Specification: 99% min Genistein Powder

Sample: Genistein Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: Light Yellow Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Genistein Powder Usage and Synthesis.

Genistein, mainly in the legume family, such as acacia horn, Yam bean root in large quantities.

Genistein, i.e. goldfinch isoflavin, this product is rectangular or hexagonal rod-shaped crystals (60% ethanol), dendritic crystals (ether), melting point 297-298 ℃ (slightly decomposed). Soluble in DMSO and ethanol, almost insoluble in water, solubility in water is 8.7 micrograms / ml, change the solution pH has no significant effect on the dynein lignin.

Uses and functions of Genistein.

Genistein has estrogenic and anti-estrogenic properties, has antioxidant effects, can inhibit the activity of tyrosine protein kinase (PTK), can inhibit the activity of topoisomerase II, has the effect of inducing programmed cell death, improving the efficacy of anticancer drugs, and inhibiting angiogenesis, and so on, and it is a promising cancer chemopreventive agent, and its anticancer effects and mechanisms have a wide range of application prospects.

1、It has estrogenic and anti-estrogenic properties.

2, In the body can inhibit colon cancer, breast cancer, skin cancer, prostate cancer, etc.

3、It has inhibitory effect on many kinds of tumour cell lines.

4、It has antioxidant effect

5、It can inhibit the activity of tyrosine protein kinase (PTK)

6、It can inhibit the activity of topoisomerase Ⅱ.

7, Can prevent postmenopausal osteoporosis

8、It can induce programmed cell death, improve the efficacy of anticancer drugs and inhibit angiogenesis, etc. It is a promising cancer chemopreventive agent, and its anticancer effect and mechanism have a wide range of application prospects.

Pharmacological Effect of Genistein.

Goldfinch isoflavone, also known as genistein, is a polyphenolic compound that can be found in plants such as soybeans and red clover, with a molecular structure similar to 17β-estradiol, antioxidant properties and a high affinity for the estrogen receptor, which inhibits the activity of tyrosine protein kinase (PTK) and topoisomerase II, and has the effect of inducing programmed cell death, increasing the efficacy of anticancer drugs, and inhibiting angiogenesis, it is a type of flavonoid (also called isoflavone).

Often found with isoflavones called soy glycogen, they are both known as soy isoflavones. These compounds have been extensively studied for their health benefits and are a promising cancer chemopreventive agent with significant impact in the prevention of cancer and other diseases. Genistein is the main phytoestrogen being studied.

Clinical applications of Genistein Powder.

It can be used for women's skin care and health care as well as the prevention of blood diseases and cancer.

Goldfinch isoflavones have polyphenol hydroxyl structure, the hydrogen atom on the phenolic hydroxyl group is easy to detach from the oxygen atom under the external action, forming hydrogen ions and exerting a reducing effect, which is the structural basis for genistein to be able to antioxidant and have a reducing effect.

Therefore, such substances in food can fight against superoxide anion free radicals, block the chain reaction of free radicals, and play an antioxidant role.

Genistein is not a hormone, but it is called phytoestrogen because of its ability to bind to the estrogen receptor to exert a weak estrogenic effect.

Because the activity of isoflavones is 1/1000 of estradiol, and estradiol competitive binding estrogen receptor, showing two-way regulation, the estrogenic effect is much lower than the harmful effect of estradiol, and thus has a protective effect on hormone-related diseases, such as menopausal syndrome, osteoporosis, elevated blood lipids, etc.; for high estrogen levels, the performance of anti-estrogenic activity to prevent and control breast cancer, endometritis, has a two-way regulation, and has a two-way regulation of endometritis. endometritis, with two-way regulation and balance function.

Goldfinch isoflavones on trinitrotoluene WR1339-induced hyperlipidaemia in rats, there is a reduction in its serum cholesterol and triglyceride effect, for the latter is particularly significant.