Ecdysone Raw Materials Ecdysone Powder

CAS:3604-87-3

MF:C27H44O6

MW:464.63

EINECS:222-760-4

Specification: 99% min Ecdysone Powder

Sample:Ecdysone Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance:White

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Ecdysone Powder Usage and Synthesis.

1.Promotion of nucleic acid and protein synthesis The earliest studies of ecdysterone were on its anabolic effects.

2.Effects on glucose metabolismThe effects of ecdysterone on mammals, including effects on glucose metabolism, are mediated through the cAMP-protein kinase system.

3.Promotion of lipid metabolismThe regulatory effect of ecdysterone on lipid metabolism is related to the action of ecdysterone on the cAMP-protein kinase system.

4.Immunomodulatory effect of ecdysterone on rat peritoneal cavity mast cells histamine release inhibition may be related to its inhibitory effect on the mobilisation of intracellular calcium

storage.

5. The effect on the central nervous system ecdysterone as an insect growth and metabolism regulating hormone for higher animals also has a wide range of pharmacological effects, and the toxic side effects are small, in the plant world is also very widely distributed. The in-depth study of the pharmacological effects of ecdysterone can not only provide the basis for the mechanism of action of many traditional Chinese medicines.

Uses of Ecdysone.

1. In medicine, ecdysteroids can promote protein synthesis, exclude cholesterol from the body,lower blood lipids, inhibit the rise of blood sugar and other physiological activities. It is used in

folk medicine for the treatment of rheumatoid arthritis.

2. In sports health care products, ecdysone can stimulate the translation and migration process of muscle cell protein growth by increasing the assembly of amino acids into protein chains.

3. In cosmetics, ecdysteroids can remove aged keratin and oil, clean pores, and prevent acne and blackheads; they also reduce the appearance of fine lines and wrinkles, improve skin elasticity, even skin tone, and lighten pigmentation.

4. In the breeding industry, ecdysteroids can promote the moulting process of insects,amphibians and so on.

Preparation of Ecdysone.

A method for extracting ecdysterone from plants, characterised by the following steps:

a. The raw material is crushed, add biological enzymes at 40-50 ℃ under the condition of enzymatic digestion 2-3 hours, add water to warm up to 70-80 ℃, keep warm and soak for 1-2 hours, extracted 2-3 times, filtration of the extract;

b. The above extracts are added to the ultrafiltration membrane ultrafiltration, the permeate is then added to the nanofiltration membrane concentration, the concentrated liquid is added to the same volume of ethanol solution filtration, and then added to the ethyl acetate extraction, the residual liquid is added to  the activated charcoal reflux Decolourisation, decolourisation solution is filtered and concentrated to alcohol-free crystals, the crystals are dried to obtain ecdysterone.

Pharmacological Effect of  Bulk Ecdysone Powder.

Ecdysone acts on the human body to promote collagen synthesis, anti-arrhythmia, anti-fatigue; promote cell growth, stimulate dermal cell division, exclude cholesterol in the body; lowering

blood lipids, inhibit the rise of blood glucose; promote menstruation and activate collaterals,dehumidification and analgesia, and other physiological activities. It is a natural anti-cancer agent. Dew grass ecdysteroid since its introduction in 1976, has developed irregular tablets,injections, creams.

Folk for rheumatoid arthritis, treatment of different symptoms of rheumatism and arthritis patients have better efficacy of its active ingredient 20-hydroxy ecdysterone by clinical research has proved to have a direct hypoglycaemic effect on type II diabetes mellitus, the total effective rate of 84%, to improve the diabetes mellitus patients, "more than three, less than one" symptom is particularly obvious.