Ecdysone Raw Materials Powder Ecdysone

CAS:3604-87-3

MF:C27H44O6

MW:464.63

EINECS:222-760-4

Specification: 99% min Ecdysone Powder

Sample:Ecdysone

Packaging:1kg/bag, 25kg/drum

Brand: Raw Materials

Appearance:white

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Ecdysone Powder Usage and Synthesis.

1. Promote the synthesis of nucleic acids and proteins. The earliest research on ecdysterone was about its assimilation.

2. Effects on glucose metabolism. The effects of ecdysterone on mammals, including the effects on glucose metabolism, are mediated by the cAMP-protein kinase system.

3. Promote lipid metabolism. The regulatory effect of ecdysterone on lipid metabolism is related to the effect of ecdysterone on the cAMP-protein kinase system.

4. Immunomodulatory effect. The inhibitory effect of ecdysterone on histamine release from mast cells in the peritoneal cavity of rats may be related to its inhibitory effect on the mobilization of intracellular calcium storage.

5. Effects on the central nervous system. As an insect growth metabolism regulating hormone, ecdysterone also has a wide range of pharmacological effects on higher animals, and has few toxic and side effects. It is also widely distributed in the plant kingdom. In-depth research on the pharmacological effects of ecdysterone can not only provide a basis for the mechanism of action of many traditional Chinese medicines.

Uses and functions of Ecdysone.

The ecdysteroid hormone has physiological activities such as promoting collagen synthesis, resisting arrhythmia, and resisting fatigue; promoting cell growth, stimulating dermal cell division, and eliminating cholesterol in the body; lowering blood lipids, inhibiting blood sugar rise; promoting blood circulation, removing dampness and relieving pain.

It is a natural anti-cancer preparation. Since the advent of dew grass ecdysteroid hormone in 1976, irregular tablets, injections, and ointments have been developed.

It is used in folk medicine for rheumatoid arthritis and has a good effect on the treatment of rheumatism and arthritis patients with different symptoms. Its effective ingredient 20-hydroxyecdysterone has been proven by clinical studies to have a direct blood sugar-lowering effect, with a total effective rate of 84% for type II diabetes, and is particularly effective in improving the "three more and one less" symptoms of diabetic patients.

Preparation of Ecdysone.

A method for extracting ecdysterone from plants, characterized by the following steps:

a. crushing the raw material, adding biological enzymes to hydrolyze at 40-50℃ for 2-3 hours, adding water to raise the temperature to 70-80℃, keeping warm and soaking for 1-2 hours, extracting 2-3 times, and filtering to obtain an extract;

b. adding the above extract to an ultrafiltration membrane for ultrafiltration, adding the permeate to a nanofiltration membrane for concentration, adding an equal volume of ethanol solution to the concentrate for filtration, then adding ethyl acetate for extraction, adding activated carbon to the raffinate for reflux decolorization, filtering and concentrating the decolorized solution to alcohol-free crystals, and drying the crystals to obtain ecdysterone.

Product method of Bulk Ecdysone Powder.