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Supply Selamectin Raw Materials powder
Product Overview:
Seramectin (also known as seramectin) is produced by the fermentation of a new strain of Streptomyces aviviae, which is genetically modified by Pfizer in the United States. It is obtained by chemically synthesizing and structurally modifying Dolamectin. It was first released in the United Kingdom in July 1999 under the brand name Revolution.
Supply Selamectin Raw Materials powder Attributes
CAS:220119-17-5
MF:C43H63NO11
MW:769.97
EINECS:815-979-7
Specification: 99% min Selamectin
Sample:Selamectin powder
Packaging:1kg/bag, 25kg/drum
Brand: Henrikang
Appearance:white
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
Supply Selamectin Raw Materials powder Details
Selamectin of Usage and Synthesis.
The mechanism of action of seramectin is the same as that of other abamectin drugs. On the one hand, seramectin can act as an agonist of GABA to trigger the release of presynaptic GABA, thus causing the increase of membrane permeability to Cl¯; on the other hand, the drug can open the chloride ion channels controlled by glutamate, resulting in the increase of Cl¯ permeability leading to membrane potential hyperpolarization. Thus blocking the transmission of nerve signals, causing rapid, fatal and non-spastic neuromuscular paralysis and death. Since flukes and tapeworms do not have GABA neurotransmitter and glutamate-controlled Cl¯ channels, these drugs have no repellent effect on them. The drug binding site of invertebrates is in peripheral tissues, while the drug binding site of mammals is in the central nervous system. Due to the effect of the blood-brain barrier, such drugs rarely enter the brain tissue, so such drugs are safe for most mammals.
Uses of Selamectin.
The safety of seramectin has been greatly improved, and both oral and injection have good effects. Seramectin is a kind of in vivo and in vitro insecticide mainly for adult fleas, filaria and mange in pet cats and dogs.
Preparation of Selamectin.
Product method of Bulk Selamectin Powder.
