Raw material intermediate Danofloxacin mesylate Powder

CAS:119478-55-6

MF:C20H24FN3O6S

MW:453.48

EINECS:638-813-3

Specification​: 99% min Danofloxacin mesylate Powder

Sample: Danofloxacin mesylate Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White to Off-White

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Danofloxacin mesylate Powder Usage and Synthesis.

Darifloxacin mesylate has strong antibacterial effects mainly against Gram-positive bacteria (G+), certain anaerobes and mycoplasmas. It is sensitive to Streptococcus aureus, Streptococcus haemolyticus, Pneumococcus, Legionella pneumophila, Mycoplasma, and also sensitive to Clostridium difficile, Clostridium weissei, Tetanus bacillus, and Mycobacterium avium.

Uses of Danofloxacin mesylate.

For infections of livestock (G+) bacteria, certain anaerobes, mycoplasma and spirochetes.

1. lung infections caused by a mixture of Staphylococcus aureus, Streptococcus haemolyticus, Pneumococcus, Legionella pneumophila.

2. avian chronic respiratory disease caused by Mycoplasma, porcine asthma.

3. proliferative enteritis, spirochete dysentery, toxoplasmosis in pigs; 4. necrotising enteritis in chickens.

4. necrotising enteritis in chickens; 5. actinomycosis in pets.

5. pet actinomycosis.

Pharmacological Effects of Danofloxacin mesylate.

Darifloxacin mesylate has strong antibacterial effects mainly against Gram-positive bacteria (G+), certain anaerobes and mycoplasmas. It is sensitive to Streptococcus aureus, Streptococcus haemolyticus, Pneumococcus, Legionella pneumophila, Mycoplasma, and also sensitive to Clostridium difficile, Clostridium weissei, Tetanus bacillus, and Mycobacterium avium.

Dafloxacin mesylate is clinically used for infections caused by epimycin-resistant and erythromycin-resistant bacteria; mycoplasma infections caused by avian chronic respiratory disease and porcine asthma; necrotising enteritis in chickens; porcine dense spirochete dysentery, toxoplasmosis; pet actinomycosis.

In vitro studies of Danofloxacin mesylate.

Danofloxacin is a synthetic antimicrobial agent of the fluoroquinolone class that acts primarily through inhibition of bacterial DNA-promoter enzymes, which are necessary for DNA super-helixation to provide proper spatial arrangement of DNA in the bacterial cell.The minimum inhibitory concentration (MIC) of Danofloxacin, resistant to 90 per cent (MIC90) contemporary European and North American regional Pasteurellahaemolytica, Pasteurellamultocida and Haemophilussomnus, the most important respiratory pathogens of livestock, was 0.125 µg/ml