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Pharmaceutical sulfamonomethoxine Raw Materials Powder CAS 1220-83-3 sulfadimethoxine API Factory Su
Product Overview:
Sulfamonomethoxine is one of the most powerful antibacterial drugs among sulfonamides. It is a white or off-white crystalline powder, odourless, almost tasteless, and darkens gradually when exposed to light. It can be used to inhibit most gram-positive and negative bacteria. This product belongs to the broad-spectrum antibacterial drugs, is the most antibacterial activity in vitro and in vivo sulfonamides, most of the gram-positive and negative bacteria have a strong inhibition, the bacterial resistance to this drug is slow. It has good antibacterial effect on both Gram-positive and negative bacteria, such as Streptococcus pyogenes, Salmonella Chemicalbook, and Bacillus pneumoniae.
Sulfamonomethoxine is structurally similar to p-aminobenzoic acid, and can compete with aminobenzoic acid for the enzyme dihydrofolate synthase in the bacterial body, hindering the synthesis of dihydrofolate, and ultimately affecting the synthesis of nucleic acids, and inhibiting bacterial growth and reproduction. sulfamonomethoxine's effect can be antagonised by aminobenzoic acid and its derivatives (procaine, bupivacaine). In addition, pus as well as tissue decomposition products provide substances essential for bacterial growth and antagonise sulfamonomethoxine.
Pharmaceutical sulfamonomethoxine Raw Materials Powder CAS 1220-83-3 sulfadimethoxine API Factory Su Attributes
CAS:1220-83-3
MF: C11H12N4O3S
MW: 280.3
EINECS: 624-483-8
Specification: 99% min sulfamonomethoxine Powder
Sample: sulfadimethoxine Powder
Packaging:1kg/bag, 25kg/drum
Brand: Henrikang
Appearance: White Powder
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
Pharmaceutical sulfamonomethoxine Raw Materials Powder CAS 1220-83-3 sulfadimethoxine API Factory Su Details
Sulfamethoxazole, i.e. Sulfanilamide-6-methoxypyrimidine, has a strong antibacterial effect, and also has a significant effect on coccidia and toxoplasmosis. It is easily absorbed internally, with low acetylation rate, not easy to produce crystal urine and haematuria, and is used for the treatment of various sensitive bacterial infections and avian coccidiosis and toxoplasmosis in pigs.
It has the strongest effect on Streptococcus, Pneumococcus, Salmonella, Bartonella, Corynebacterium septicum, Escherichia coli, and also has antimicrobial effect on Staphylococcus, Bacillus deformans Chemicalbook, Bacillus anthracis, etc. Therefore, it is widely used in respiratory, gastrointestinal and urinary tract infections of livestock and poultry.
However, it is more commonly used for emergency treatment of outbreaks of leucocytosis and coccidiosis in poultry. It is also highly effective against toxoplasmosis in pigs. This product is a newer long-acting sulfonamides, the antibacterial spectrum is similar to sulfadiazine, but the antibacterial effect and protection against animal infections are stronger than other sulfonamides.
Uses and functions of sulfamonomethoxine Powder.
Sulfonamides for infections of haemolytic streptococci, pneumococci and meningococci .
As a broad-spectrum antimicrobial agent, sulfamethoxazole is effective against haemolytic streptococci, pneumococci and Escherichia coli. It is mainly used for the treatment of urinary tract infections, respiratory tract infections, and also has a killing effect on Mycoplasma, Worker and coccidiosis in animals.
Pharmacological Effects of sulfamonomethoxine Powder.
This product is the strongest antibacterial effect of sulfonamides in vitro and in vivo, it has strong inhibitory effect on most gram-positive and negative bacteria, and the bacteria are slow to develop resistance to this drug. It is mainly used for various diseases caused by sensitive bacteria, toxoplasmosis and erythrocytes (e.g. hyperthermia, streptococcus, haemophilus parvovirus, toxoplasmosis, porcine oedema, erythrocytosis, infectious pleuropneumonia, bacillus pneumonia, etc.) and their mixed infections. The absorption rate of intramuscular injection of this product is as high as 99.5% or more, with high blood concentration and maintenance of action for more than 48 hours.
Production method of sulfamonomethoxine Powder.
Produced from dibutyl malonate by cyclisation, condensation, etherification, acidification, etc.
