Paracetamol Aspirin Raw Materials Powder

CAS:50-78-2

MF: C9H8O4

MW: 180.16

EINECS:200-064-1

Specification​: 99% min Aspirin Powder

Sample: Aspirin Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Aspirin Powder Usage and Synthesis.

Acetylsalicylic acid also known as aspirin is an antiplatelet aggregation drug. Antithrombotic: This product has an inhibitory effect on platelet aggregation, which can prevent thrombosis, and is clinically used to prevent thrombosis after transient

ischaemic attack, myocardial infarction, atrial fibrillation, artificial heart valve, arteriovenous fistula, or other surgeries. It is also used in the treatment of unstable angina.

Uses and functions of Aspirin.

Aspirin is the earliest, most widely used and most common antipyretic and analgesic antirheumatic drug.With antipyretic, analgesic, anti-inflammatory, anti-rheumatic and anti-platelet aggregation and other aspects of the pharmacological effects, play a role in the rapid efficacy of the drug, the efficacy of certain, overdose easy to diagnose and deal with, and seldom occur allergic reactions.

It is commonly used in cold and fever, headache, neuralgia, arthralgia, muscle pain, rheumatic fever, acute endocrine arthritis, rheumatoid arthritis and toothache. Acetylsalicylic acid is a variety listed in the National Essential Drug Catalogue and is also an intermediate of other drugs.

Salicylic acid and acetic acid. Slightly soluble in water, soluble in ethanol, ether, chloroform, also soluble in alkali hydroxide solution or carbonic acid solution, while decomposition. Commonly used antipyretic and analgesic. Used for antipyretic,analgesic, antirheumatic, promoting excretion of uric acid in gout patients, anti-platelet aggregation and biliary roundworm treatment.

Pharmacological Effects of Voriconazole.

Acetylsalicylic acid (aspirin) is a traditional antipyretic and analgesic drug that also has antiplatelet aggregation properties.Acetylsalicylic acid (Aspirin) has antithrombotic properties in vivo and reduces the formation of obstructive thrombi in peripheral arteries.

It inhibits the platelet release response as well as the release of endogenous ADP, 5-HT, etc. Thus, inhibits the second-phase aggregation of platelets without inhibiting their first-phase aggregation.The mechanism of action of acetylsalicylic acid (aspirin) is to acetylate the cyclooxygenase of platelets, thereby inhibiting the formation of intracyclic peroxides and the production of TXA2.

It also acetylates platelet membrane proteins and inhibits platelet membrane enzymes, which also helps to inhibit platelet function.Because of the inhibition of cyclooxygenase, it affects the synthesis of PGI2 in the blood vessel wall; it also inhibits the

enzyme of platelet TXA2 synthesis, such as in large doses, it is the production of both TXA2 and PGI2 that is affected.

It is suitable for ischaemic heart disease, after coronary artery transplantation (PTCA), after coronary artery bypass grafting,

it can prevent transient cerebral ischaemia, stroke, myocardial infarction, and reduce the incidence of arrhythmia.

Production method of Aspirin Raw Powder.

Acetylation of salicylic acid: in the reaction tank with acetic anhydride (add 0.7889 times the total amount of salicylic acid),and then add two-thirds of the amount of salicylic acid, stirring temperature, at 81-82 ° C reaction of 40-60min. cooling to 81-82 ° C insulation reaction 2h. Check the free salicylic acid qualified, lower the temperature to 13 ° C, precipitation of crystals, dumping filtration, washed and dried, at 65-70 ° C airflow. Dry, get acetylsalicylic acid.