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Cephalosporin antibiotics for veterinary use Ceftiofur Hcl Powder
Product Overview:
Ceftiofur is the third generation of cephalosporins for veterinarians developed in the United States in the 1980's. The drug was first marketed in the United States in 1988, and due to its excellent antimicrobial activity and pharmacokinetic characteristics, it has been formally approved for the treatment of respiratory diseases in beef cattle, dairy cattle, horses, pigs, and sheep in the United States, Canada, Japan, and a number of countries in Europe.
Appearance is off-white to light yellow powder. Insoluble in water, slightly soluble in acetone, almost insoluble in ethanol.
Cephalosporin antibiotics for veterinary use Ceftiofur Hcl Powder Attributes
CAS:103980-44-5
MF:C19H18ClN5O7S3
MW:560.01
EINECS:600-507-2
Specification: 99% min Ceftiofur Hcl Powder
Sample:Ceftiofur Hcl Powder
Packaging:1kg/bag, 25kg/drum
Brand: Henrikang
Appearance:White Powder
Storage: Cool Dry Place
Shelf Life: 2 Years
Test Method: HPLC
Cephalosporin antibiotics for veterinary use Ceftiofur Hcl Powder Details
Ceftiofur Hcl Powder Usage and Synthesis.
Cephalosporin is contraindicated in persons with a history of hypersensitivity to cephalosporin. Cephalosporin cross-reacts with other endocannabinoid antibiotics (e.g., penicillins, cephalosporins, carbapenems), and therefore should be used with caution in those who are allergic to the above antibiotics. Systemic antibiotics should not be given orally to patients with sepsis, shock or other serious illnesses, as the absorption of the drug from the gastrointestinal tract slows down or decreases significantly at this time, and the drug should be given by injection (static injection is preferred).
Uses and functions of Ceftiofur Hcl.
Ceftiofur Sodium / Ceftiofur Hydrochloride is indicated for the treatment of respiratory diseases (transport fever, pneumonia) in cattle caused by Pasteurella haemolytica, Pasteurella multocida, Haemophilus somnolentis, both in lactation and non-lactation.
Ceftiofur sodium can be used for equine respiratory disease caused by Streptococcus equi subspecies pestis, and ceftiofur hydrochloride can be used for hoof rot in cattle. In pigs, both are used to control/treat bacterial pneumonia.
Ceftiofur sodium is also indicated for respiratory disease in sheep and goats and for susceptible urinary tract infections in dogs, and is potentially useful in the treatment of other small animal infections, as well as for use in newborn chicks and turkeys.
Pharmacological Effect of Ceftiofur Hcl.
Ceftiofur hydrochloride is rapidly decomposed into furoic acid and defuranoyl ceftiofur, which is active and inhibits cell wall synthesis in sensitive proliferating bacteria (phase III), and has an antimicrobial spectrum similar to that of cefotaxime. Ceftiofur has a wide antimicrobial range in vitro and is effective against many pathogens, including Bartonella, Streptococcus, Staphylococcus, Salmonella, Escherichia coli and many other genera.
Pharmacodynamics of Bulk Ceftiofur Hcl Powder.
