Veterinary Medicine Amikacin Sulfate CAS 39831-55-5 Raw Powder

CAS: 39831-55-5

MF: C22H45N5O17S

Specification​: 99% min Amikacin Sulfate

Sample:  Amikacin Sulfate Powder

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Amikacin Sulfate Powder Usage and Synthesis:

Amikacin Sulfate Powder is a semi-synthetic aminoglycoside antibiotic, Estradiol Undecylate CAS 3571-53-7 is an anti-infective agent. Amikacin Sulfate Powder is a white or off-white crystalline powder, easily soluble in water. Amikacin Sulfate Powder is used for livestock and poultry digestive tract infection, piglets yellow and white dysentery, swine dysentery, swine atrophic rhinitis, aquatic bacterial septicemia, enteritis, erysipelas, ascites. Butamycin sulfate is a semi-synthetic aminoglycoside antibiotic with an antibacterial spectrum similar to that of gentamicin, and is effective against Pseudomonas aeruginosa, Pseudomonas aeruginosa, Escherichia coli and Proteus mirabilis. Amikacin sulfate (BB-K8) is a semi-synthetic, water-soluble aminoglycoside derivative of kanamycin that binds to the 30S ribosomal subunit of bacteria and causes mRNA reading errors, resulting in the inability of bacteria to synthesize proteins necessary for their own growth.

Pharmacokinetics of Amikacin Sulfate Powder:

Amikacin sulfate is an aminoglycoside antibacterial agent. It mainly inhibits the synthesis of bacterial proteins and makes them lethal. It has strong Antibacterial activity against various Gram-negative and positive bacteria, Pseudomonas aeruginosa, etc. It is stable to the blunt enzymes (acetyltransferase, phosphotransferase and nucleosidyltransferase) produced by various intestinal negative bacteria and Pseudomonas aeruginosa, and it is often sensitive to this product when the bacteria are resistant to other aminoglycosides.Amikacin Sulfate Powder is used for serious infections caused by Pseudomonas aeruginosa and some other Pseudomonas species, Escherichia coli, Aspergillus spp., Klebsiella spp. and other sensitive Gram-negative bacilli with Staphylococcus spp. such as bacteremia or sepsis, bacterial endocarditis, lower respiratory tract infections, bone and joint infections, biliary tract infections, etc. Amikacin Sulfate Powder is also used for the treatment of serious infections caused by Gram-negative bacilli resistant to kanamycin, gentamicin or tobramycin strains because it is stable to most aminoglycoside blunting enzymes.

1、Amikacin sulfate and penicillins, cephalosporins, lincomycin, TMP, the efficacy is enhanced.  

2, Amikacin sulfate with alkaline drugs (such as sodium bicarbonate, aminophylline, etc.) borax, the efficacy is enhanced, but the toxicity is also enhanced. 

3, Amikacin sulfate with vitamin C, vitamin B with reduced efficacy, with aminoglycosides, cephalosporins, toxicity enhanced.

Clinical Application of Amikacin Sulfate Powder:

Amikacin Sulfate Powder, commonly used in formulations such as injections. It is an aminoglycoside antibiotic. It is used for serious infections caused by Pseudomonas aeruginosa and some other Pseudomonas aeruginosa, Escherichia coli, Aspergillus spp., Klebsiella spp. and other sensitive Gram-negative bacilli and Staphylococcus spp. such as bacteremia or sepsis, bacterial endocarditis, lower respiratory tract infections, bone and joint infections, biliary tract infections, etc. It is also used to treat serious infections caused by Gram-negative bacilli resistant to kanamycin, gentamicin or tobramycin strains because it is stable to most aminoglycoside blunting enzymes.

Amikacin sulfate is used for respiratory, urinary tract, abdominal, soft tissue, bone, joint, reproductive system infections and sepsis caused by G-bacteria, such as

1, livestock and poultry digestive tract infections, peritonitis, oviductitis, chicken dysentery, E. coli disease, infectious gastroenteritis, pseudomonas aeruginosa, staphylococcal disease.

2, piglets yellow and white dysentery, swine dysentery, swine atrophic rhinitis.

3, aquatic bacterial septicemia, enteritis, erysipelas, ascites.

Amikacin sulfate is an Anti-infective drug used to treat urinary tract infection, sepsis, skin infection, bone and joint infection, pneumonia and lower respiratory tract infection caused by sensitive bacteria.