Veterinary Medicine Ceftriaxone Sodium Powder CAS 74578-69-1 Raw Materials

CAS: 74578-69-1

MF: C18H19N8NaO7S3

MW: 578.57

EINECS:  277-930-0

Specification​: 99% min Ceftriaxone Sodium

Sample: Ceftriaxone Sodium Powder

Packaging:1kg/bag, 25kg/drum

Brand: Henrikang

Appearance: White Powder

Storage: Cool Dry Place

Shelf Life: 2 Years

Test Method: HPLC

Portal:https://henrikang.en.made-in-china.com/

Ceftriaxone Sodium Powder Usage and Synthesis.

Ceftriaxone Sodium Powder is a water-soluble beta-lactam cephalosporin.Veterinary Medicine Ceftriaxone Sodium is a non-gastrointestinal, semi-synthetic, broad-spectrum, long-acting, third-generation cephalosporin antibiotic used for the treatment of respiratory infections,

urinary tract infections, gonorrhoea, and for preoperative Ceftriaxone Sodium Raw Materials is used for the treatment of respiratory tract infections, urinary tract infections, biliary tract infections caused by sensitive pathogens, as well as abdominal infections, pelvic infections, skin and soft tissue infections, bone and joint infections, septicaemia, meningitis, etc., and the prevention of perioperative infections.

Uses and functions of Ceftriaxone Sodium Powder.

Ceftriaxone sodium is a water-soluble β-lactam cephalosporin, a non-gastrointestinal, semi-synthetic, broad-spectrum, long-lasting third-generation cephalosporin antibiotic, very sensitive to most Gram-positive and negative bacteria, with a broad antibacterial spectrum, strong antibacterial effect, resistance to enzymatic degradation, low toxicity, strong tissue penetration, and long half-life. 

The β-lactam structure of ceftriaxone acts on the carboxypeptidase, peptide chain endonuclease, transpeptidase of bacterial cytoplasmic membrane, these enzymes are involved in cell synthesis and cell division, which leads to cell wall defects and cell death, and inhibits mucopeptide synthesis of bacterial cell wall to achieve the therapeutic effect, and it has achieved good therapeutic effect in the treatment of lower respiratory tract infections, skin tissues, urinary tract infection, bone and joint infections, as well as bacterial septicemia. Good therapeutic effect.

Pharmacological Effects of Ceftriaxone Sodium Powder.

This product is a third generation cephalosporin antibiotic. It has strong activity against Enterobacteriaceae. The MIC90 for Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Flouraudi citrobacter, indole-positive Aspergillus, Prevotella spp. and Serratia spp. ranged from 0.12 to 0.25 mg/L. 

Enterobacter cloacae, Enterobacteriaceae spp. and Pseudomonas aeruginosa were poorly susceptible to the product. It has strong antibacterial effect on Haemophilus influenzae, Neisseria gonorrhoeae and Neisseria meningitidis, and also has good effect on Streptococcus haemolyticus and Pneumococcus. 

The MIC for Staphylococcus aureus is 2-4mg/L. Methicillin-resistant Staphylococcus aureus and Enterococcus are resistant to the product. The majority of S. fragilis are resistant to this product.

Production method of Ceftriaxone Sodium Powder.

Ceftriaxone sodium is a 3rd generation cephalosporin antibiotic with broad-spectrum and high efficacy, it is bactericidal against many Gram-positive, negative and anaerobic bacteria, and its antibacterial effect is enhanced by its high degree of stabilisation against most of the β-lactamases produced by bacteria.