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The main ingredient of Paeonia lactiflora extract is paeoniflorin, which can be widely used not only in the medical field, but also in the cosmetic industry.
White peony extract is a highly effective inhibitor of PDE4 activity, through the inhibition of PDE4 activity, can make a variety of inflammatory and immune cells (such as neutrophils, macrophages, T lymphocytes and eosinophils, etc.) cAMP to reach a concentration sufficient to inhibit inflammatory cell activation and play an anti-inflammatory role.
It also has analgesic, antispasmodic, anti-ulcer, vasodilator, increase organ blood flow, antibacterial, hepatoprotective, detoxification, anti-mutagenic, anti-tumour and so on.
Uses of White Peony Extract.
Calming the liver and relieving pain, nourishing blood and regulating menstruation, astringing Yin and stopping sweating. It is used for headache and dizziness, dystocia, abdominal pain, contracture of limbs, blood deficiency, impotence, menstrual irregularities, spontaneous sweating, night sweating.
(1) Antipyretic effect: paeoniflorin has antipyretic effect on mice with artificial fever, and reduces the normal body temperature of mice.
(2) Enhancement of memory: paeoniflorin has improved the learning and memory acquisition of mice induced by scopolamine.
( (3) Antihypoxia: Paeoniflorin can prolong the survival time of mice in normobaric hypoxia, reduce the overall oxygen consumption of mice, and reduce the mortality of mice in potassium cyanide toxic hypoxia.
Pharmacological Effect of White Peony Extract.
1.Anti-inflammatory, antibacterial and antiviral effects White peony extract has a significant inhibitory effect on rat egg white acute inflammatory oedema, and inhibit the proliferation of cotton ball granuloma.
White peony total glucoside has anti-inflammatory and organism-dependent immunomodulatory effects on adjuvant arthritic rats.
White peony preparations have some inhibitory effect on staphylococcus, haemolytic streptococcus, diplococcus pneumoniae, dysentery bacillus, typhoid bacillus, Vibrio cholerae, Escherichia coli and Pseudomonas aeruginosa.
In addition, 1:40 Paeonia lactiflora decoction can inhibit Jingke 68-1 virus and herpes virus.
2.Hepatoprotective effect White peony extract has obvious antagonistic effect on D-galactosamine-induced liver injury and SGPT elevation, which can reduce SGPT and normalise the lesions and necrosis of hepatocytes The effect of ethanol extract of Paeonia lactiflora on D-galactosamine-induced liver injury and SGPT increase is obvious.
The ethanol extract of Paeonia lactiflora has a reducing effect on the total activity of lactate dehydrogenase and isoenzymes elevated in acute liver injury caused by aflatoxin in rats.
The total glucoside of Paeonia lactiflora can inhibit the elevation of SGPT and lactate dehydrogenase in mice caused by carbon tetrachloride, and has an antagonistic effect on the eosinophilic degeneration and necrosis of liver tissue.
3.Antioxidant effect of white peony extract TGP has antioxidant and cell membrane stabilisation effects, free radicals may have scavenging effects.
4.Cardiovascular system effect of white peony extract can dilate isolated heart coronary blood vessels, against acute myocardial ischaemia induced by post-pituitary leptin in rats, for arterial injection so that the peripheral vascular resistance decreased, blood flow increased.
Paeoniflorin also has a dilating effect on coronary blood vessels and peripheral blood vessels, and cause a decrease in blood pressure.
Some studies have shown that paeoniflorin, an extract of Paeonia lactiflora, has an inhibitory effect on ADP-induced platelet aggregation in vitro or in rats.
Chemical Components of Bulk White Peony Extract Powder.
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