Natural Drynaria Fortunei Extract Powder

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Drynaria Fortunei Extract Powder Usage and Synthesis.

Boneset Extract is the dried rhizome extract of the mistletoe fern Drynariafortunei (Kunze) J. SM. of the family Bonesetaceae, the main active substance is naringenin, and it also contains methyl eugenol, protocatechuic acid, new North American sacred herbs glycosides, boneset dihydroflavonoid glycosides, cyclic wood pineapple stanol acetate, cyclic hydroxylated keelbone stanol acetate, cyclic opuntia stanol acetate, rapeseed sterols, and other chemical compounds. Chemical substances.

It has the effect of promoting proliferation and differentiation, anti-osteoporosis, anti-inflammation, promoting fracture healing, dental osteoclast protection, renal protection, prevention and treatment of drug-induced deafness, and lowering blood lipids.

The hydrated extract of Osteoglossum methanol has inhibitory activity on elastase, which can be used as cosmetic and medicine for the treatment of skin aging, allergy, inflammation and pigmentation.

Uses of Drynaria Fortunei Extract.

Boneset extract can treat osteoarthritis and other related diseases by inhibiting apoptosis and regulating the level of inflammatory factors.

In addition, Boneset has the efficacy of reducing drug toxicity. The decoction in water has obvious detoxification efficacy on the toxic side effects caused by kanamycin and streptomycin, and can reduce the toxic effect of kanamycin on cochlea, and has certain preventive effect on the ototoxicity of the drug, and it can also protect the kidneys, and reduce the damage of kanamycin on the kidneys.

The dihydroflavone glycosides contained in this drug can significantly eliminate or attenuate the hypnotic effect of isobarbital on mice.

Sodium isobarbital is mainly metabolised in the liver by hepatic drug enzymes, and dihydroflavonoid glycosides have an inducing effect on hepatic drug enzymes, so it may be through the activation of hepatic drug enzymes. Therefore, Boneset is also a liver detoxifier.

Boneset can also benefit bones, increase blood calcium and blood phosphorus levels, improve cartilage cells, and is suitable for adjuvant treatment in the middle stage of fracture.

In addition, Boneset is also effective in strengthening muscles and bones, stopping bleeding and relieving pain, and can be used to assist kidney deficiency, tinnitus , lumbar and knee weakness, fracture damage or loose and painful teeth and other symptoms.

In conclusion, Boneset Extract has a variety of benefits and effects, but needs to be used under medical supervision.

Pharmacological Effect of Drynaria Fortunei Extract.

1. Hypolipidemic effect of bone marrow supplement alcohol extract intramuscular injection can prevent high fat feed caused by rabbits serum cholesterol, triglyceride increase, can make has increased the lower, and prevent the formation of aortic atherosclerosis plaque, but also can make the liver and adrenal cholesterol within the obvious decline.

Osteoglossum polysaccharides also has obvious anti-hyperlipidaemia and anti-atherosclerosis effect on rabbits, and promotes the recovery of damage to mitochondria and rough endoplasmic reticulum of hepatocytes and adrenal cells caused by hypercholesterolaemia, thus promoting the conversion and discharge of cholesterol in liver and adrenal cells.

Dihydroflavonoid glycosides on serum cholesterol, triglycerides also have a tendency to reduce.

2. Promote fracture healing effect of bone marrow extract can promote bone calcium absorption, and improve blood calcium and blood phosphorus levels, thereby facilitating fracture healing. With the bone Ⅱ pill (the main containing bone broken bones) to cause artificial fracture of rabbits, can make the haematoma absorption, mechanization, scab growth and remodelling type in advance, the bone endothelial growth is particularly active, osteoclasts activity enhancement.

For experimental arthritis in young rats, treatment with osteochondritis dissecans decoction can improve the function of chondrocytes, delay the degenerative changes of cells, and reduce the rate of osteoarthropathy.

3. Reduce the role of antibiotic toxicity with streptomycin 600mg/kg intraperitoneal injection given to guinea pigs, a group of five guinea pigs were not given Bone Broken Patch died, another group of seven in the injection before the infusion of Bone Broken Patch decoction (equivalent to 100g/kg of the raw drug) only 2 deaths, suggesting that the Bone Broken Patch can significantly reduce the mortality rate of animals caused by streptomycin poisoning.

In addition, Boneset can also significantly reduce the damage of kanamycin to the ear.

Chemical Components of Bulk Drynaria Fortunei Extract Powder.

1. Flavonoid compounds flavonoids and their glycosides: the compounds are mainly kaempferol and lignans as glycosides of flavonoid glycosides.

Dihydroflavonoids and their glycosides:The dihydroflavonoids in Boneset are mainly North American saint herb, naringenin, and bitter ginseng flavonoids and their glycosides. Naringin is an important active ingredient in Boneset.

Flavanols and their glycosides:The compounds with catechin, aflatoxin and epigallocatechin as the main components and the flavanol glycosides with epigallocatechin as the glycoside were isolated from Boneset.

2. Triterpenoids compounds isolated from Boneset are mostly obtained from the mineral oil ether extracts of Boneset: lambda-(11)-ene, libetenol, cycloLaurethral, cycloLaurethral, libetenol, libetenoic acid, hepa-21-ene, northeastern guanzhuol, hebei-guanzhuol acetate, pah-22(29)-ene, and Chiratone.

3. Compounds of the phenylpropanoid group were isolated from Osteocarpine to obtain ferulic acid-β-D-glucopyranoside (E)-4-O-β-D-glucopyranosyl caffeic acid, -coumaric acid-4-O-β-D-glucopyranoside, sodium trans-caffeate, dihydroisoferulic acid, dihydrocaffeic acid, and (E)-p-pinacolate-β-B-glucopyranoside.

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