Broad-spectrum bacteriostasis Chlorhexidine Diacetate raw Materials powder

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Chlorhexidine Diacetate powder Usage and Synthesis.

Step 1: Disinfectant

It is used to wash hands before operation, soak in 0.02% aqueous solution (1:5000) for 3min, and disinfect the surgical field with 0.5% alcohol solution (containing 70% alcohol), its efficacy is similar to iodine tincture, and can also be used to disinfect surgical instruments with 0.1% aqueous solution (0.5% sodium nitrite added to prevent rust). Storage equipment can be soaked in 0.02% aqueous solution (containing 0.1% sodium nitrite), and replaced once every 2 weeks. And skin or wound disinfection with 1% spray spray, or 0.05% water solution to wash the wound, etc.

2. Urological and gynecological drugs

The compound preparation containing chlorhexidine gluconate 1.2mg and metronidazole 0.2mg per milliliter is used for vaginal irrigation to treat various vaginitis and leucorrhea abnormalities caused by bacteria, trichomoniasis and mold. Its pharmacological effect is chlorhexidine, also known as chlorhexidine, a broad spectrum fungicide; Metronidazole, also known as Medrol, has anti-anaerobic bacteria and anti-trichomoniasis effects. There are also compound chlorhexidine acetate suppository for anaerobe, trichomoniasis vaginitis or mixed infections.

3. Oral medicine

Compound chlorhexidine gargaries are used for the adjuvant treatment of gingival bleeding, periodontal abscess and oral mucosal ulcer caused by gingivitis, pericoronitis and oral mucositis, and for the control of oral infection after dental surgery.

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Uses of Chlorhexidine Diacetate.

Cationic broad-spectrum antimicrobial, belonging to the biguanide family. Its mechanism of action involves disturbing the cell membrane of bacteria. Also disinfectant. It has strong bactericidal effect on gram-positive bacteria, negative bacteria and fungi, and is also effective on Pseudomonas aeruginosa. It can be used to disinfect skin, rinse wounds, and also to disinfect surgical instruments. A highly effective and safe antibacterial disinfectant for external use, which can kill Staphylococcus aureus, Escherichia coli and Candida albicans.

Pharmacological action of Chlorhexidine Diacetate.

Product Methods of Chlorhexidine Diacetate.

It is prepared by diazotization, condensation, elimination, denitrification, condensation, neutralization and salt formation of p-chloroaniline.

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