Phenylbutazone raw material Phenylbutazone Powder

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Phenylbutazone Powder Usage and Synthesis.

Polytaxone is a drug that acts on the central nervous system, belonging to pyrazolone derivatives, with weak antipyretic and analgesic effects and strong anti-inflammatory effects, it is effective for inflammatory pain and can promote the excretion of uric acid.

The antipyretic and analgesic effect of pau taisone is less than that of acetylsalicylic acid, and the toxicity is greater, so it is not generally used as an antipyretic and analgesic, but its anti-inflammatory effect is stronger, and it can be used for the treatment of rheumatoid and rheumatoid arthritis, acute gouty arthritis,ankylosing spondylitis.

Uses and functions of Phenylbutazone.

It has antipyretic and analgesic, anti-inflammatory and anti-rheumatic effects, and is mainly used in thetreatment of rheumatic and rheumatoid arthritis and gout.

Used in the treatment of rheumatoid arthritis and gout.

Pharmacological Effect of Phenylbutazone.

POTEZONE is a kind of drug acting on the central nervous system, belongs to pyrazolones derivatives, weak antipyretic and anti-inflammatory effect is stronger, the effect on inflammatory pain is good, and can promote the excretion of uric acid.

The antipyretic and analgesic effect of pau taisone is not as good as acetylsalicylic acid, and the toxicity is larger, so it is generally not used as antipyretic and analgesic, but its anti-inflammatory effect is stronger,and it can be used for the treatment of rheumatoid and rheumatoid arthritis, acute gouty arthritis,ankylosing spondylitis.

In addition, it can reduce the reabsorption of urate from renal tubules and has a mild urinary excretion effect, and can also be used in patients with acute gout. Often need to be given continuously or used in conjunction with other drugs.

It can also be used to treat acute schistosomiasis, filarial acute lymphadenitis, tuberculosis, malignant tumours and other causes of fever.

Recent studies have found that the mechanism of anti-inflammatory, analgesic and anti-rheumatic effects of pau taisone is not due to pituitary-adrenal excitation, may be due to the drug in the inflammatory tissues to inhibit the production of inflammation of the relevant active substances, such as the synthesis of prostaglandins, leukocyte activity and metastasis, the release of lysosomal enzymes and their activity;analgesic may also be a result of the inhibition of prostaglandin synthesis.

Product Methods of Bulk Phenylbutazone Powder.

It is obtained by cyclisation of hydrogenated azobenzene with diethyl butylmalonate. Hydrogenated azobenzene, diethyl butylmalonate, sodium methanol and sodium sulphite are heated together and refluxed vigorously for 1.5h to give birth to the sodium salt of potexon, and then acidified with acetic acid to obtain potexon.

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