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Rutin, a member of the genus Vitamin P, is a glycoside of dehydroflavanone. It is a hydrogen transporter and may be involved in the action of oxidoreductases in the body, influencing the activity of the thyroid gland and protecting adrenaline from oxidation.
In the body it enhances the action of vitamin C and promotes its accumulation in the body. It maintains the elasticity of blood vessels, reduces their permeability and decreases their fragility.
Mechanism for hyaluronic acid is the composition of capillary wall cell interstitial matrix components, when it is hydrolysed by hyaluronidase, the resistance of the capillary is reduced, permeability and fragility increase, easy to cause bleeding.
Rutin can inhibit hyaluronidase, preventing hydrolysis of hyaluronic acid, thus enhancing the resistance of capillaries and reducing their permeability and fragility.
Rutin also has the ability to promote cell proliferation, prevent blood cell agglutination, as well as diuretic, antitussive, hypolipidemic, antihypertensive, protect the ulcer surface, anti-inflammatory and anti-allergic effects.
Uses and Function of Sophorin.
1. Food colouring (like lemon yellow); antioxidant; nutritional supplement. Mainly used in cold drinks, beverages, pastries, processed meat products, processed aquatic products and so on.
2. Vitamin drugs. Used in the prevention and treatment of hypertensive cerebral hemorrhage, diabetic retinal Chemicalbook hemorrhage and hemorrhagic purpura, etc., also used as food antioxidant and pigment.3. It has anti-inflammatory effect; Vitamin P-like effect, has the effect of maintaining vascular resistance, lowering its permeability, reducing the brittleness, etc., and has the effect of expectoration of fat on fatty infiltration of the liver, and the expectoration of fat with the combination of glutathione is more obvious; anti-virus effect and the effect of inhibition of aldol
Used in the prevention and treatment of hypertensive cerebral haemorrhage, diabetic retinal haemorrhage and haemorrhagic purpura, etc. It is also used as food antioxidant and pigment.
3. It has anti-inflammatory effect; vitamin P-like effect, with the maintenance of vascular resistance, reduce its permeability, reduce the role of brittleness, etc., fat infiltration of the liver has a fat effect, and glutathione combined with fat effect is more pronounced; antiviral effect and inhibit the role of aldose reductase.
System of Sophorin.
The raw materials (generally with acacia buds) crushed, extracted with hot ethanol, and then by ether, hot methanol and hot water for many times crystallised and refined.
The residue obtained after the concentration of extracts, with a solvent to remove other soluble pigments and other impurities, and then by ethanol, ether, hot methanol and hot water for many times by crystallisation and activated charcoal refining and high purity.
Product Method of Bulk Sophorin Powder.
Rutin exists in the rue leaves, tobacco, orange peel, tomatoes, etc., acacia rice and buckwheat flowers are particularly rich in content. China's medicinal rutin is extracted from acacia rice.
Sophora rice after washing, with hot water and milk of lime (pH to 7.5-8) boiled for 20min, add borax, at 95-100 ℃ insulation for half an hour, filtered while hot, with hydrochloric acid will be adjusted to pH 6-7 filtrate, cooled to below 30 ℃, static precipitation crystals, separation, crude rue glucoside, after dissolution, recrystallisation, drying that is the finished product. Total yield 8.3% by acacia rice.
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