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There is an isomerase (2-arylpropionyl-CoA epimerase) in the body that converts (R)-isobutylpropionic acid to (S)-(+)-isobutylpropionic acid. Because of this, and because of the high cost of synthesising compounds with special optical selectivity, only racemic products are currently on the market. Dextro Ibuprofen is the right-handed form of Ibuprofen, a non-steroidal antipyretic, analgesic, and anti-inflammatory drug, and the right-handed form is more potent than the racemic and levitra forms. In the body, 60% of the levosome, can be converted to the dextrosome, for for the overall level of the drug to provide an active reserve.
Uses and functions of dexibuprofen Powder.
Antipyretic and analgesic anti-inflammatory drugs.
Pharmacological dexibuprofen Raw Materials Powder.
(S)-(+)-Ibuprofen(HCT-15andHCA-7cells;0-1000µM;8days)treatmentreducesconcentrationdependentlycellsurvivalinbothcelllinestoasimilarextent.(S)-(+)-Ibuprofen(HCT-15andHCA-7cells;0-1000µM;20-72hours)treatmentcausesaG0/G1phaseblockaswellasapoptosis.(S)-(+)-Ibuprofen(HCT-15andHCA-7cells;9Chemicalbook00µM;4-72hours)treatmentshowsadownregulationofcyclinAandBandanincreaseofthecellcycleinhibitoryproteinp27Kip-1.(S)-(+)-IbuprofeninhibitsCOXactivity,thromboxaneformation,andplateletaggregation.(S)-(+)-IbuprofeninhibitstheactivationofNF-κBinresponsetoT-cellstimulationwithanIC50of61.7μM.
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