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Alpha-Amylase Powder Usage and Synthesis:
Alpha-Amylase Powder, also known as starch-1,4-dextrinase, is one of the most widely used enzyme preparations in industrial production. It is officially named α-1,4-D-glucan-glucoside hydrolase, Since the C1 carbon atom of the reducing terminal glucose residue of the hydrolyzate is in the α configuration, it is called α-amylase. When Alpha-Amylase Powder acts on starch, it can cut α-1,4-glucosidic bonds from the interior of starch, glycogen, oligomeric or polysaccharide molecules in a random manner to produce maltose, oligosaccharides and glucose.
Pharmacokinetics of Alpha-Amylase Powder:
The microorganisms producing this enzyme mainly include Bacillus subtilis, Aspergillus niger, Aspergillus oryzae and Rhizopus. Alpha-Amylase Powder, like other enzymes, has reaction substrate specificity, and amylase reaction substrates from different sources are also different. Usually, Alpha-Amylase Powder shows the highest specificity for starch and its derivatives. These Starch and its derivatives include amylopectin, amylose, cyclodextrin, glycogen and maltotriose, etc.
Clinical Application of Alpha-Amylase Powder:
α-amylase is a metalloenzyme, and many metal ions, especially heavy metal ions, can inhibit it; Acetic acid, BSA, EDTA and EGTA have significant inhibitory effects on α-amylase. Among them, α-amylase contains at least one Ca2+, and Ca2+ can keep the enzyme molecule in an appropriate conformation, thereby maintaining its maximum activity and stability. Ca2+ has a stronger affinity for α-amylase than other ions, and the number of calcium ions it binds is between 1-10. Alpha-Amylase Powder is used in the pharmaceutical industry: As Aspergillus niger a-amylase has acid resistance, it can be used to make drugs to help digestion, and develop acid-resistant a-amylase suitable for gastric acidic environment, which is used to prepare digestive aids agent.
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