Amisulpride Raw Materials Powder CAS 71675-85-9

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Amisulpride Powder Powder Usage and Synthesis:

Amisulpride is an atypical antipsychotic drug used in the treatment of acute delusional psychosis, paranoid progressive schizophrenia, as well as in the treatment of defective states of schizophrenia, residual psychotic evolution, and depressed states with retardation. The efficacy of amisulpride in treating the negative symptoms of dysphoria and schizophrenia is believed to be due to its blocking of presynaptic D2 receptors, which is done by blocking or antagonizing the receptor. To de-inhibit the release of dopamine, as with most other approved antipsychotics, amisulpride is thought to act by reducing dopamine D2 receptor signaling. Amisulpride is Active Pharmaceutical Ingredients Raw Material

Pharmacokinetics of Amisulpride Powder:

Amisulpride/Amisulpride is a benzamide derivative with high and equal affinity for D2 and D3 receptor subtypes and lack of affinity for pentraxinergic, adrenergic, and cholinergic receptors. What has generated the most interest is its clinical effectiveness, with amisulpride having the clinical characteristics of all second-generation antipsychotics (pentraxin/dopamine receptor or multi-receptor blockers), minimal extrapyramidal side effects better improvement of positive and negative symptoms and better overall efficacy in long-term follow-up studies. It is a selective D2/3 receptor blocker. In preclinical studies, a degree of selectivity and first-occupancy effect on presynaptic D2/3 autoreceptors was observed at small doses.

Clinical Application of Amisulpride Powder:

Amisulpride tablets are used to treat acute or chronic schizophrenia with predominantly positive or negative symptoms (e.g., unresponsiveness, emotional indifference, and social withdrawal), as well as schizophrenia characterized by negative symptoms. Specific D2/D3 receptor antagonist for the treatment of positive and negative symptoms in acute and chronic schizophrenia. Amisulpride is a chemical compound with the molecular formula C17H27N3O4S. For amisulpride, elevated concentrations of dopamine act on D1 receptors, thereby relieving the negative symptoms of poor mood and schizophrenia.Our company also supplies other pharmaceutical ingredients for the treatment of psychiatric disorders

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