Amitriptyline Hydrochloride CAS 549-18-8 Powder

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Amitriptyline Hydrochloride Powder Usage and Synthesis:

Amitriptyline Hydrochloride is an antidepressant with antidepressant and strong sedative effects. It is mainly used for endogenous and exogenous depressive symptoms, menopausal depression, neurotic depression and depressive symptoms of organic psychosis, and also for enuresis in children and adolescents. It is mainly used for the treatment of various depressive disorders with a relatively strong sedative effect and for the treatment of anxiety and motor depression. Anticholinergic reactions, such as excessive sweating, dry mouth, blurred vision, urinary difficulties, constipation and other central nervous system can occur during treatment.

Pharmacokinetics of Amitriptyline Hydrochloride Powder:

Amitriptyline Hydrochloride is an inhibitor of serotonintransporter (SERT) and norepinephrinetransporter (NET) with Ki values of 3.45 nM and 13.3 nM, respectively.AmitriptylineHCl also AmitriptylineHCl also inhibits histaminereceptorH1, histaminereceptorH4, 5-HT2 and sigma1receptor, corresponding to Ki values of 0.5nM, 7.31nM, 235nM and 287nM, respectively.Amitriptyline is a tricyclic antidepressant. Adverse effects appear as drowsiness, tremor, vertigo, and also postural hypotension, occasional seizures, bone marrow suppression, and toxic liver damage. Severe heart disease, myocardial infarction, epilepsy, glaucoma, urinary retention, hyperthyroidism, and hepatic impairment should be noted. In addition, it is contraindicated in patients with allergies and should not be taken with hormonal drugs.

Clinical Application of Amitriptyline Hydrochloride Powder:

Amitriptyline Hydrochloride is a tricyclic antidepressant that inhibits the reuptake of 5-hydroxytryptamine and norepinephrine, with stronger inhibition of 5-hydroxytryptamine reuptake and stronger sedative and anticholinergic effects. It is used for the treatment of various depressive disorders. It has a strong sedative effect and is mainly used for the treatment of anxious or agitated depression. It has antidepressant effect and strong sedative effect. Antidepressant for all types of depression and depressive symptoms of organic psychosis. It is mainly used for endogenous exogenous depressive symptoms, menopausal depression, neurotic depression and depressive symptoms of organic psychosis, and also for enuresis in children and adolescents. Our company is a well-known exporter of pharmaceutical raw materials in China.

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