Enalapril maleate Raw material powder Enalapril maleate

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Enalapril maleate Powder Usage and Synthesis.

1. For essential hypertension, it can be used alone or combined with other antihypertensive drugs.

2. For congestive heart failure, it can be used alone or in combination with cardiotonic drugs and diuretics.

Uses of Enalapril maleate.

Essential hypertension at all stages; Renal vascular hypertension; For patients with symptomatic heart failure, this product is also suitable for improving the survival rate, delaying the progression of symptomatic heart failure, and reducing hospitalization due to heart failure; For the prevention of symptomatic heart failure, for the prevention of coronary ischemic events in patients with asymptomatic left ventricular dysfunction, this product is suitable for reducing the incidence of myocardial infarction and reducing hospitalization caused by unstable angina pectoris.

Pharmacological action of Enalapril maleate.

Enalapril maleate is a potent, mercapto-free inhibitor of angiotensin-converting enzyme (ACE), which is hydrolyzed to Enalaprilat in vivo to inhibit ACE. The mechanism of action is the conversion of angiotensin I to angiotensin II, which weakens the vascular smooth muscle tone, reduces the secretion of aldosterone, and lowers blood pressure. Its blood pressure lowering effect is 10 times stronger than captopril, and it is longer lasting. Its antihypertensive effect is slow and lasting. Its hemodynamic effect is similar to that of captopril, which can reduce total peripheral vascular resistance and renal vascular resistance and increase renal blood flow. Long-term application can reverse left ventricular hypertrophy and improve ventricular remodeling.

Product Method of Bulk Enalapril maleate Powder.

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